An over-the-counter (OTC) drug product needs to be analyzed to determine if it is adulterated. The product is a complex mixture of ingredients that have a wide range of solubilities. The active ingredient is non-volatile and has a λmax at 280 nm and emits light at 360 nm. The other ingredients in the product absorb light at 280 nm but do not emit light. Select the most appropriate analysis technique based on the information provided. a) fluorescence spectroscopy b) absorbance spectroscopy c) HPLC with absorbance detection d) HPLC with fluorescence detection
An over-the-counter (OTC) drug product needs to be analyzed to determine if it is adulterated. The product is a complex mixture of ingredients that have a wide range of solubilities. The active ingredient is non-volatile and has a λmax at 280 nm and emits light at 360 nm. The other ingredients in the product absorb light at 280 nm but do not emit light. Select the most appropriate analysis technique based on the information provided. a) fluorescence spectroscopy b) absorbance spectroscopy c) HPLC with absorbance detection d) HPLC with fluorescence detection
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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An over-the-counter (OTC) drug product needs to be analyzed to determine if it is adulterated. The product is a complex mixture of ingredients that have a wide range of solubilities. The active ingredient is non-volatile and has a λmax at 280 nm and emits light at 360 nm. The other ingredients in the product absorb light at 280 nm but do not emit light. Select the most appropriate analysis technique based on the information provided.
a) fluorescence spectroscopy
b) absorbance spectroscopy
c) HPLC with absorbance detection
d) HPLC with fluorescence detection
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