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Q: List 10 characteristics of an ideal antimicrobial drug.
A:
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An antimicrobial drug with a therapeutic index is a better
choice than one with a therapeutic index.
a. low, high
b. high, low
Step by step
Solved in 2 steps
- A broad- spectrum antimicrobial drug would be a drug that attacks many different microbial sites. True or false.What is meant by a therapeutic window of a drug? b. Is it beneficial for a drug to have a wide or narrow therapeutic window? Motivate your answerChoose the combination of answers that most accurately completes the statement. An antimicrobial drug with a ___________ therapeutic index is a better choice than one with a ___________ therapeutic index. a. low, high b. high, low
- Choose the combination of answers that most accurately completes the statement. Which statement is not an aim in the use of drugs in antimicrobial chemotherapy? The drug should a. have selective toxicity b. be active even in high dilutions c. be broken down and excreted rapidly d. be microbicidalWhich of the following is not a factor that should be considered when selecting a antimicrobial drug? A. The nature of the microbe causing the infection B. The overall medical condition of the patient C. The origin of the drug D. The degree of susceptibility of the microbe to that drugExplain the role of different toxicological parameters (i.e. ED50, TD50, LD50, NOAEL, LOAEL, etc.) in ensuring the safety of a drug candidate. explain this in 600-1000 words,please explain at your own words
- Choose the false statement below: O Using three different classes of antimicrobials in combination greatly decreases the chance of developing resistance because the drug resistance strategy for one is the same for others. O Drug resistance to antimicrobials has proven to be extensive against chemotherapeutics as well as other chemical antimicrobials. O Collateral damage is a term that refers to the killing of normal body flora as well as pathogenic bacteria when taking antimicrobials or antibiotics.List 10 characteristics of an ideal antimicrobial drug.Pick a pathogen, suggest tests that should be performed on that pathogen to determine the specific drugs and give reasons why they would be appropriate. (Terminology to incorporate: narrow-spectrum, broad-spectrum, MIC, Kirby-Bauer, therapeutic index, selective toxicity, drug mechanism)
- The list below choose all the concerns surrounding antimicrobial use. A. toxicity B. disruption of normal flora C. allergic reactions D. tolerance of effective doseWhen two antimicrobial drugs are used at the same time, antagonistic effects can occur. Which of the following is NOT a possible antagonistic effect of combining two antimicrobial drugs? Increased elimination of one drug Increased activity of both drugs Increased toxicity Decreased therapeutic levels Decreased activity of both drugsExplain the role of different toxicological parameters (i.e. ED50, TD50, LD50, NOAEL, LOAEL, etc.) in ensuring the safety of a drug candidate. Briefly explain this at your own words