Answered: Please read the case file from exercise…

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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Question

Please read the case file from exercise 25 (pg. 145). What information stood out to you after reading this? Why is it important for the antimicrobial susceptibility test to be performed? Please explain by using one of the patients from the case study to give support to your answer.

**Antimicrobial Susceptibility Testing (Kirby-Bauer Method)**

**Learning Outcomes**

Antimicrobial susceptibility testing has been ordered for three patients.

**Case File**

**Patient A**, a 4-year-old boy, was complaining that his throat hurt when his parents picked him up from daycare. He was found to have a temperature of 39°C (102.2°F), a red throat, and some swelling of the lymph nodes in his neck. A whitish exudate was on his tonsils. No skin rash was visible. On a blood agar plate, tests showed signs of group A *Streptococcus* (exercise 43). He was empirically started on amoxicillin. Because of previous problems while treating ear infections (otitis media) with amoxicillin, tests for antibiotic sensitivity were ordered. Additionally, biochemical tests to identify the causative organism of infection following a burn, in addition to a post-surgical infection, are being used to identify the organism. A multistep system is being used to identify the likely organism as a possible source of the hospital-acquired infection, with DNA analysis.

Transcribed Image Text:**Antimicrobial Susceptibility Testing (Kirby-Bauer Method)** **CASE FILE** Antimicrobial susceptibility testing has been ordered for three patients. - **Patient A**, a 4-year-old boy, was complaining that his throat hurt when his parents picked him up from day care. He was brought in for an examination. He was found to have a temperature of 39°C (102.2°F), a red throat, and some swelling of the lymph nodes in his neck. A whitish exudate was seen on his tonsils. No skin rash was visible. Diagnostic tests were ordered. A throat swab was taken for culture on a blood agar plate (exercise 14) and a rapid immunoassay for group A *Streptococcus* (exercise 34). He was empirically started on amoxicillin. Because of previous problems while treating ear infections (otitis media), an antibiotic sensitivity test was ordered. - **Patient B** is showing symptoms of infection following a burn. In addition to biochemical tests to identify the causative organism (exercise 23), an antibiotic sensitivity test was ordered, as the likely causative organism is difficult to treat. - **Patient X** has developed a postsurgical infection. A multitest system is being used to identify the causative organism (exercise 34). As the infection may be hospital-acquired, tracing of the possible source of the infection is being done with DNA analysis (exercise 27). **LEARNING OUTCOMES** At the completion of this exercise, students should be able to: - Demonstrate how to perform antimicrobial susceptibility testing using the Kirby-Bauer method. - Understand the origin of a zone of inhibition and how it should be interpreted. **Diagram/Graph Explanation** There is no diagram or graph in the provided image, just textual information and a logo of an antibiotic tablet with dosing instructions.

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