Answered: although polydactyly is a common limb…

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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although polydactyly is a common limb malformation observed in humans and other species, no modern tetrapods have evolved a polydactylous phenotype as their predominant limb structure. Please present one hypothesis that explains this paradox, and describe how it does. (hypothesis should involve discussion of cellular-level processes, gene regulatory mechanisms, limb/digit patterning, and/or digit functions)

Expert Solution

Step 1

Limb is devoloped from the limb field in the embryo. Limb has mainly three regions

Proximal (stylopod
Middle zengopod
Distal autopod

The shoulder to the finger axis is denoted as the proximal distal axis , the thumb small finger axis as the anterior posterior axis and the dorsal ventral axis specified by the knuckles palm region.

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