Acyl transfer (nucleophilic substitution at carbonyl) reactions proceed in two stages via a "tetrahedral intermediate." Draw the tetrahedral intermediate as it is first formed in the following reaction. 0 OH CI + H₂N • You do not have to consider stereochemistry. • Include all valence lone pairs in your answer. • Do not include counter-ions, e.g., Na+, I, in your answer. In cases where there is more than one answer, just draw one. A ChemDoodle Activate Windows

Organic Chemistry: A Guided Inquiry
2nd Edition
ISBN:9780618974122
Author:Andrei Straumanis
Publisher:Andrei Straumanis
Chapter20: Acidity And Pka Of Phenols
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Acyl transfer (nucleophilic substitution at carbonyl) reactions proceed in two stages via a "tetrahedral
intermediate." Draw the tetrahedral intermediate as it is first formed in the following reaction.
0
OH
CI
+
H₂N
• You do not have to consider stereochemistry.
• Include all valence lone pairs in your answer.
• Do not include counter-ions, e.g., Na+, I, in your answer.
In cases where there is more than one answer, just draw one.
A
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Transcribed Image Text:Acyl transfer (nucleophilic substitution at carbonyl) reactions proceed in two stages via a "tetrahedral intermediate." Draw the tetrahedral intermediate as it is first formed in the following reaction. 0 OH CI + H₂N • You do not have to consider stereochemistry. • Include all valence lone pairs in your answer. • Do not include counter-ions, e.g., Na+, I, in your answer. In cases where there is more than one answer, just draw one. A ChemDoodle Activate Windows
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