ACTIVITY NO. 6 CAPILLARY FRAGILITY TEST (Rumple Leede Test) 1. What stage/s in hemostasis is evaluated by Tourniquet Test? 2. Explain briefly the role of the following factors in maintaining vascular integrity. 2.1 Platelets 2.2 Vitamin C
ACTIVITY NO. 6 CAPILLARY FRAGILITY TEST (Rumple Leede Test) 1. What stage/s in hemostasis is evaluated by Tourniquet Test? 2. Explain briefly the role of the following factors in maintaining vascular integrity. 2.1 Platelets 2.2 Vitamin C
ACTIVITY NO. 6 CAPILLARY FRAGILITY TEST (Rumple Leede Test) 1. What stage/s in hemostasis is evaluated by Tourniquet Test? 2. Explain briefly the role of the following factors in maintaining vascular integrity. 2.1 Platelets 2.2 Vitamin C
1. What stage/s in hemostasis is evaluated by Tourniquet Test?
2. Explain briefly the role of the following factors in maintaining vascular integrity.
2.1 Platelets
2.2 Vitamin C
3. Give 3 examples for each of the following bleeding disorders associated with vascular abnormalities
3.1 Connective Tissue Defects
3.1.1 Hereditary
3.1.2 Acquired
3.2 Altered Vessel Wall Structure
3.2.1 Hereditary
3.2.2 Acquired
4. Give a brief description of the following term related to hemostasis.
4.1 Purpura
4.2 Ecchymosis
4.3 Hematoma
5. Illustrate and label the different steps of Rumple Leede Test.
(picture for reference if answers cannot be found please refer to useful websites)
Transcribed Image Text:Learning Outcome:
At the end of the LABORATORY REPORT, the learner is expected to:
1. Efficiently perform the process of doing a capillary fragility test.
2. Know the clinical importance of performing a capillary fragility test for patients with
bleeding disorders.
EXPERIMENT NO. 6: CAPILLARY FRAGILITY TEST
Principle:
The capillary fragility test is also known as the Tourniquet test, Rumpel-Leede Test, Hess test.
This test evaluates capillary integrity. It is used to aid in the clinical diagnosis of hemorrhagic fever
syndromes such as Dengue Fever.
Petechiae occur as a result of increased capillary fragility (microvessels easily rupture and a small
amount of bleeding occurs in the skin) or thrombocytopenia (causing spontaneous bleeding in the
skin). There are more accurate tests to indicate platelet count and function. Petechiae are small,
round, nonraised red spits in the skin.
Production of petechiae can be induced in patients who have increased capillary fragility or
thrombocytopenia. There are two methods of inducing petechiae. The most common is with positive
pressure. A blood pressure cuff is applied to an extremity and inflated above venous pressure. The
second way is with negative pressure. A suction cup is applied to an area of skin for a particular
period of time. Patients with thrombocytopenia, poor platelet function, or purpura will develop more
than 10 petechiae per square inch of skin. The number of petechiae can be graded from few with
confluent (1 to 4).
Indications:
Assessment of platelet-vessel wall interactions.
Reference Range:
Negative or 1+.
Within a radius of 2.5 cm:
Females = 10 or less petechiae
Males = 5 or less petechiae
REFERENCES:
Turgeon, M. L. (1993). Clinical hematology: Theory and procedures. Boston: Little, Brown.
Pagana, K. D., Pagana, T. J., & Pagana, T. N. (2015). Mosby's diagnostic and laboratory
test reference (12th ed.). St. Louis, Mo.: Mosby.
Walters, N. J., Estridge, B. H., & Reynolds, A. P. (1990). Basic medical laboratory
techniques (2nd ed.). Albany, NY: Delmar.
Transcribed Image Text:Materials:
PROCEDURE
CAPILLARY FRAGILITY TEST (Rumple Leede Test)
1. Blood Pressure Apparatus
2. Stopwatch
Procedure:
1. Apply Blood Pressure cuff to the upper arm.
2. Initiate the BP cuff at a pressure halfway between the systolic and diastolic pressure and
leave it for 5 minutes.
3. Remove the BP cuff from the arm and examine the forearm, hand and finger for petechia.
4. Report as follows:
0-10 petechia
11-20 petechia
21-50 petechia
51 and above
+1
+ 2
+3
+4
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