1) Explain in details how and by what mechanisms tachycardia and hypotension affect myocardial oxygen supply. in ischemic heart disease. 2) What is the mechanism of action for beta blockers in treatment of angina (List at least three actions that leads to a decrease in oxygen demand)? 3) Complete the following chart by identifying the side effects of each class of medication (Simply check mark the side effects apply to each specific class of drugs). Class of drugs Tolerance Nitrate Non DHP CCB DHP CCB Beta blocker Bradycardia Reflex Tachycardia 4) Complete the chart designating which of the following medications are indicated for each of the three clinical conditions (Simply check mark the indication applies to each specific class of drugs). Class of drugs Chronic Stable Acute Coronary Angina Vasospastic Angina Syndrome Beta Blocker Calcium Channel Blocker Nitrates Thrombolytic (fibrinolytic) Bonus Question: Why are nitrates such as isosorbide mononitrate not indicated in the management of hypertension?

1) Explain in details how and by what mechanisms tachycardia and hypotension affect myocardial oxygen supply. in ischemic heart disease. 2) What is the mechanism of action for beta blockers in treatment of angina (List at least three actions that leads to a decrease in oxygen demand)? 3) Complete the following chart by identifying the side effects of each class of medication (Simply check mark the side effects apply to each specific class of drugs). Class of drugs Tolerance Nitrate Non DHP CCB DHP CCB Beta blocker Bradycardia Reflex Tachycardia 4) Complete the chart designating which of the following medications are indicated for each of the three clinical conditions (Simply check mark the indication applies to each specific class of drugs). Class of drugs Chronic Stable Acute Coronary Angina Vasospastic Angina Syndrome Beta Blocker Calcium Channel Blocker Nitrates Thrombolytic (fibrinolytic) Bonus Question: Why are nitrates such as isosorbide mononitrate not indicated in the management of hypertension?

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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