Activation of the CAP protein, inactivation of the Lac Repressor, activation of the TRP Repressor, and noncompetitive feedback inhibition of a metabolic/enzymatic pathway, all require
Q: What is the source of energy for protein translocation into the ER? Choose one: 1. the action of…
A: Introduction Translation is the process by which ribosomes in the cytoplasm or endoplasmic reticulum…
Q: A mutation in E. coli makes the lac operator unable to bind the active repressor. How would this…
A: Lac operon is a set of three genes present in bacteria and the genes are responsible for…
Q: E) The regulatory protein that controls expression of the hexose operons is a transcriptional…
A: The regulatory protein that controls expression of the hexose operons is a transcriptional…
Q: Using the lac operon as a model, explain the role of inducers, repressors, and inducer exclusion.
A: Genomic DNA (deoxyribonucleic acid) consists of both structural and regulatory genes. The structural…
Q: Describe the regulation of the lac operon when lactose is present and glucose is absent
A: In 1961, F. Jacob and J. Monod proposed the operon model to explain the genetic basis of enzyme…
Q: How does the presence of lactose activate genes necessary for its catabolism? O lacl will bind…
A: The lactose sugar is metabolized in the bacterial cells by means of an operon called the lac operon.…
Q: Describe the mechanism by which cAMP receptorprotein (CRP), the regulatory protein for catabolite…
A: Operon is a functional unit of DNA that consists of cluster of genes under control of promoter.…
Q: Under what conditions is lac repressor bound to the lac operon?
A: Lactose operon (Lac operon) was discovered in Escherichia coli. This is studied to understand the…
Q: describe the actions of the normal and mutated lac operon in absence of lactose
A: The Lac operon is a group of genes with a single promoter. It takes place in prokaryotes(bacteria).…
Q: In the diagram of the lac regulation circuit below, match the numbers in the boxes with the corre…
A: In this question we have to describe about regulation of bacterial gene which is responsible for…
Q: Compare and contrast the roles of a corepressor and an inducer innegative regulation of an operon.
A: Gene regulation is the process through which the cells control the expression of genes. It controls…
Q: Explain the energetics and kinetics of specific binding between DNA and the lac Repressor
A: Lac repressor (R), is one of the first discovered transcriptional regulators and is present in the…
Q: egulatory proteins in Prokaryotes shut off transcription by binding to a site immediately in front…
A: In the given question options are given in accordance to regulation of transcription in prokaryotic…
Q: Protein activity is controlled by multiple mechanisms in the cell. Briefly describe how this type of…
A: Biomolecules are organic macromolecules that play an important role in the proper functioning of the…
Q: SigmaS is the stationary phase sigma factor. Which of the following is a likely site for RNAP-Sigmas…
A: Sigma factor- A sigma factor is a protein needed for initiation of transcription in bacteria . it…
Q: Bacteria was grown in glycerol and induced with the inducer IPTG. Explain the mechanistic steps…
A: Some strains of E. coli have the lac operon incorporated within a F' factor. The F' factor can be…
Q: Explain how glucose represses the lac operon.
A: Operons can be defined as the regions of DNA that contain the clusters of related genes. They are…
Q: Differentiate between positive and negative control, and show how both types of control operate in…
A: Controls are always part of the scientific experiments. They help researchers to conduct…
Q: Enzymes involved in the synthesis of tryptophan in bacteria is an example of Constitutive.…
A: Tryptophan is an energetically high-priced amino acid to manufacture, which makes it a crucial…
Q: In terms of the efficient use of bacterial resources, explain why it is necessary for lac operon…
A: Lactose can be broken down by E. coli bacteria to produce glucose and galactose. The lac operon…
Q: Discuss the role of GTP in the functioning of translational factors
A: Guanosine triphosphate (GTP) is one of the nucleotide that make up an RNA molecule It consists of a…
Q: The Lac operon is a common example of prokaryotic control of gene expression. In what condition is…
A: Lac operon consists of structural genes such as lacZ, lacY, and lacA which are responsible for the…
Q: Please discuss positive regulation with respect to lac operon.
A: An expression of a gene is evidenced by the synthesis of the polypeptide chain encoded by the…
Q: Interpret the level of gene expression of the lac operon, as well as the status of the lac repressor…
A: In inducible system, the end product inactivates the active repressor and the whole system turns on.…
Q: Compare and contrast the location and pH sensitivity of receptor-ligand interaction in the LDL and…
A: Endocytosis occurs when a coat protein (typically clathrin) on the cytoplasmic side of the plasma…
Q: Describe the organization of the lac operon.
A: Step 1 Inducible Operon System (Lactose Operon) is a regulated operon system in which the structural…
Q: What would most likely occur if glucosyltransferase were removed from the ER? BiP binding to…
A: Glycosyltransferases are the sub class of enzyme that catalyze the synthesis of glycosidic linkage…
Q: hat is the nature and likely location(s) of a mutant that would, 1)allow constitutive expression of…
A: The lac operon is an operon or group of genes with a single promoter (transcribed as a single mRNA).…
Q: The genes encoding the proteins involved in photosynthetis are activated and their mRNAs are made…
A: The transcription is the process of RNA production from DNA template that occurs will in the nucleus…
Q: Assume a bacterial cell has a mutation in the gene that codes for CRP, such that the mutant CRP-CAMP…
A: An operon is a set of structural genes regulated by a common promoter in bacteria.
Q: Describe the regulation of the lac operon by lac repressor and CAP.
A: Operon acts as a single regulated unit having one or more structural genes, a promoter gene, a…
Q: The Lac Operon is induced by both the presence of and the absence of in the environment.
A:
Q: Under the following conditions, what will be occurring with the lac operon? Glucose: Present…
A: lac operon is present in E.coli and contain genes that control lactose metabolism and only active…
Q: Mutations in the genes of the lac operon might affect the regulation of β-galactosidase synthesis.…
A: Lac operon is the operon system which is regulated in catabolic pathway. In this operon system,…
Q: Describe the probable genetic defect that abolishes the sensitivity of the lac operon to the absence…
A: The major carbohydrate source for bacterium are Glucose and Lactose. Glucose is is first choice of…
Q: proteih synthésis in bacteria DOES NOT require which of the following? OA Guanosine-triphosphate…
A: Protein synthesis: It is the process in which mRNA is translated into Protein. It has three steps:…
Q: Attenuation of the trp operon was viewed as a relatively inefficient way to achieve genetic…
A: Gene is the hereditary unit occupying a specific position in the chromosome and carries information…
Q: summarize the role of galactose, GAL80, GAL4, GAL3 in relation to upstream activator sequence
A: An upstream activating sequence:It is also known as upstream activation sequence or UAS. It is a…
Q: An abundance of misfolded proteins in the ER can result in the activation of the unfolded-protein…
A: Endoplasmic Reticulum can be referred to as one of the organelles of cell that can be observed in…
Q: Transcription of genes with operons is either inducible or repressible, Select one: O True False In…
A:
Q: Predict the level of genetic activity of the lac operon as well as the status of the lac repressor…
A: Operon acts as a single regulated unit having one or more structural genes, a promoter gene, a…
Q: Predict the level of gene expression of the lac operon, as well as the status of the lac represso…
A: Operon functions as a single regulated unit composed of one or more structural genes, a promoter…
Q: ERAD, or ER associated degradation, is a quality control measure with the following function: O A.…
A: Endoplasmic recticulum is a membrane bound organelle found in the eukaryotic cells. It functions in…
Q: The Bax gene, codes for a cytosolic protein that plays an important role in apoptosis. Growth factor…
A: BAX gene is a pro apoptotic member of the BCL2 gene family. Correct statements are: - BAX gene is a…
Q: Explain why inactivation of the O1 sequence of the lac operator almost completely abolishes…
A: Lac operon of the bacteria includes the structural genes that code for the enzymes involved in the…
Q: True or false: When glucose and lactose are present, the lac operon will be highly expressed
A: The lac operon is a region of the DNA where the genes responsible for the utilization of lactose as…
Q: Activation, transcription, and translation of the lac operon willrelease which exact nutrients?
A: An operon is a group of functionally-associated genes that are controlled by a shared operator.…
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- Phorbol esters have been observed to induce the transcription of AP-1–influenced genes. Explain how this processcould occur. What are the consequences of AP-1 transcription? What role does intermittent exposure to phorbol estershave on an individual’s health?If you wanted to engineer the initiator caspase from the Fas/FasL extrinsic apoptosis pathway to function in the intrinsic pathway (e.g. in response to DNA damage), which of the following would be the most likely approach to succeed? O Replace the extrinsic pathway's initiator caspase Death Effector Domain with a CARD domain O Replace the Fas Death Domain with a cytochrome C binding domain O Generate a version of the Fas receptor that localizes to the mitochondrial intermembrane space 80 O Replace the intrinsic pathway's initiator caspase CARD domain with a Death Effector Domain F3 0 $ 4 DOD DOO R F4 S % 5 T No new data to save. Last checked at 3:01pm Submit Qu B4 ♫ 8 tv A F5 < 6 MacBook Air F6 Y & 7 F7 * 8 X F8 ( 9Which of the following is a type of signal transduction pathway controlling gene expression? All of these Protein subunit dissociation pathway Receptor-associated kinase pathway None of these Cytosolic kinase pathway
- When both glucose and lactose are present (regarding the lac operon): Group of answer choices cyclic AMP is high so transcription occurs the lac repressor binds with the lactose and transcription occurs RNA polymerase is able to bind to the operator so transcription occurs cAMP is low, and transcription is turned offIn the normal cycle of Ras activity, when Ras is bound to y activity that removes a phosphate to convert GTP back to GDP and this it is inactive. Activation of Ras involves exchanging GDP for The Ras protein has intrinsic Ras. inactivates activates ATP GTP «< Questic A Moving to another question will save this response. ADP GDP GTPase Clo nucleaseWhen CAMP binds to the Catabolite Activator Protein (CAP), it causes a conformational change on the protein, which results in binding to the CAP- binding site on the DNA and molecule is known as a(n) of the lac operon. This conformational change induced by the binding of another transcription activation; allosteric effect transcription repression; binding effect translation; distortion effect mutation; interactive effect attenuation; compression effect O O O O
- bacterial cell needs to synthesize arginine if it is absent in the environment. If arginine is present in its diet, however, the cell will activate a repressor protein which blocks transcription of the genes that code for the enzymes that synthesize arginine. This is an example of which type of regulation? Group of answer choices Repressible Inducible Attenuation Post-translationalIf a bacteria cell, that has the lac operon, is metabolizing lactose O glucose is absent and allolactose has blocked the repressor. lactose is present, glucose is present, and CAP/CAMP are in contact. O glucose may be present but the inducer has blocked the repressor. O lactose is present, glucose is absent, and CAMP levels are low. Question 8 If cyclic-AMP levels are elevated (high) in a cell that has the lac operon in it's genome O glucose levels are also high. O glucose levels must be low. the cell is metabolizing the catabolic activating protein. O the cell is metabolizing glucose.Quorum sensing controls the expression of virulencein many pathogenic bacteria. Usually, pathogens express toxins in response to receptor activation by ligand binding at high cell density. V. cholerae (thecausative agent of cholera) does the opposite; its virulence genes are expressed only at low cell densitybecause its quorum-sensing receptor is repressed byligand binding. The unusual “reversed” mechanismfor activating virulence genes in V. cholerae has suggested to scientists a simple idea for generating a newkind of antibiotic for the treatment of cholera.Explain
- Which describes an enzymatic activity/biochemical function of importin-beta? facilitate release of nuclear proteins after transport through the nuclear pore complex interact with/bind to nuclear localization sequences INLSS) interact with/bind to importin-alpha hydrolyze GTP to GDP + PiA single mutation in one of the transcription factors inProblem 33 results in a drastic reduction in YFG transcription. Diagram what this mutant interaction mightlook likeErythritol is a natural sugar abundant in fruits and fermentingfoods. Pathogenic bacterial strains that catabolize erythritolcontain four closely spaced genes, all involved in erythritolmetabolism. One of the four genes (eryD) encodes a productthat represses the expression of the other three genes. Erythritolcatabolism is stimulated by erythritol. Present a regulatorymodel to account for the regulation of erythritol catabolism insuch bacterial strains. Does this system appear to be underinducibleor repressible control?