According to this diagram, why does the release of estradiol/inhibin stimulate a negative feedback loop on the anterior ptuitary gland?

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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According to this diagram, why does the release of estradiol/inhibin stimulate a negative feedback loop on the anterior ptuitary gland? Isn't the anterior ptuitary gland negatively effected only when estradiol is low, and not high?

Desmolase
Ovaries
hypothalamus
LH
Theca
Cells
GnRH
pituitary
FSH
Aromatase
Granulosa
Cells
Androstenedione
Estradiol/
Inhibin
Transcribed Image Text:Desmolase Ovaries hypothalamus LH Theca Cells GnRH pituitary FSH Aromatase Granulosa Cells Androstenedione Estradiol/ Inhibin
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