a. Rank in order of S,2 reactivity (1= most reactive) b. Rank in order of leaving group ability (1= best leaving group) NH2 H20 cr c. Rank in order of nucleophilicity (1= best nucleophile) HO.

Organic Chemistry: A Guided Inquiry
2nd Edition
ISBN:9780618974122
Author:Andrei Straumanis
Publisher:Andrei Straumanis
Chapter13: Substitution
Section: Chapter Questions
Problem 8E
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a. Rank in order of S,2 reactivity (1= most reactive)
b. Rank in order of leaving group ability (1= best leaving group)
NH2
H20
cr
c. Rank in order of nucleophilicity (1= best nucleophile)
он
Draw hypothetical reaction coordinate diagrams for:
(a) An endergonic, two-step reaction with the first step being the rate-
determining step.
(b) A reaction with three transition states and DG > 0.
Transcribed Image Text:a. Rank in order of S,2 reactivity (1= most reactive) b. Rank in order of leaving group ability (1= best leaving group) NH2 H20 cr c. Rank in order of nucleophilicity (1= best nucleophile) он Draw hypothetical reaction coordinate diagrams for: (a) An endergonic, two-step reaction with the first step being the rate- determining step. (b) A reaction with three transition states and DG > 0.
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