A vaccination is developed for a novel viral infection, and the antigen used corresponds to a short stretch of a protein found on the surface of the virus. In clinical trials, people who were exposed to the virus a second time had superior immunity to people who were given the vaccine then exposed to the virus for the first time. What is the BEST explanation for this difference? The vaccination promoted the production of all memory B cells whereas natural infection promoted the proliferation of only those memory B cells specific to the virus. The vaccination promoted the production of the correct memory B cells whereas natural infection did not. People exposed to the virus were able to make many different antibodies that bind different antigens on the virus. Vaccinations promote selection of memory B cells, whereas a natural infection triggers production of cytotoxic B cells.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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A vaccination is developed for a novel viral infection, and the antigen used
corresponds to a short stretch of a protein found on the surface of the virus. In
clinical trials, people who were exposed to the virus a second time had superior
immunity to people who were given the vaccine then exposed to the virus for the
first time. What is the BEST explanation for this difference?
The vaccination promoted the production of all memory B cells whereas natural
infection promoted the proliferation of only those memory B cells specific to the
virus.
The vaccination promoted the production of the correct memory B cells whereas
natural infection did not.
People exposed to the virus were able to make many different antibodies that
bind different antigens on the virus.
Vaccinations promote selection of memory B cells, whereas a natural infection
triggers production of cytotoxic B cells.
Transcribed Image Text:A vaccination is developed for a novel viral infection, and the antigen used corresponds to a short stretch of a protein found on the surface of the virus. In clinical trials, people who were exposed to the virus a second time had superior immunity to people who were given the vaccine then exposed to the virus for the first time. What is the BEST explanation for this difference? The vaccination promoted the production of all memory B cells whereas natural infection promoted the proliferation of only those memory B cells specific to the virus. The vaccination promoted the production of the correct memory B cells whereas natural infection did not. People exposed to the virus were able to make many different antibodies that bind different antigens on the virus. Vaccinations promote selection of memory B cells, whereas a natural infection triggers production of cytotoxic B cells.
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