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A transition mutation A. occurs when a purine is substituted for a pyrimidine or vice versa. B. results from the insertion of one or two bases into the DNA chain. C. is most frequently caused by chemicals (like acridine) that intercalate into DNA. D. results from substitution of one purine for another or of one pyrimidine for another. E. always is a missense mutation

A transition mutation A. occurs when a purine is substituted for a pyrimidine or vice versa. B. results from the insertion of one or two bases into the DNA chain. C. is most frequently caused by chemicals (like acridine) that intercalate into DNA. D. results from substitution of one purine for another or of one pyrimidine for another. E. always is a missense mutation

Biochemistry
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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QUESTION NO. 1
A transition mutation

A. occurs when a purine is substituted for a pyrimidine or vice versa.
B. results from the insertion of one or two bases into the DNA chain.
C. is most frequently caused by chemicals (like acridine) that intercalate into DNA.
D. results from substitution of one purine for another or of one pyrimidine for another.
E. always is a missense mutation

QUESTION NO. 2 

Degeneracy of the generic code denotes the existence of

A. multiple codons for a single amino acid.
B. codons consisting of only two bases.
C. base triplets that do not code for any amino acid.
D. different systems in which a given trip let codes for different amino acids.
E. codons that include one or more of the unusual bases.

QUESTION NO. 3 
Replication

A. requires that a phosphodiester bond of the incoming dNTP be hydrolyzed in order to be added to the growing chain.
B. uses 5' to 3' polymerase activity to synthesize one strand and 3' to 5' polymerase activity to synthesize the complementary strand.
C. owes its accuracy, in part, to 3' to 5' exonucleolytic activity of DNA polymerases or associated proteins.
D. begins with two dNTPs joining together.
E. requires only proteins with DNA polymerase activity.




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