A study enrolling 30  patients diasnosed with keratitis sicca (KCS) was conducted to determine the effect of a new ocular wetting agent, oker-rinse for improving ocular dryness based on rose-Bengal staining scored. patients were instructed to use oker-rinse in one eye and hypotears, as a control, in other eye 4 times a day for 3 weeks. Rose bengal staining scores were mesured as 0,1,2,3,or 4 in each of four areas of the eye: cornea, limbus, lateral conjunctiva and medical conjunctiva. higher scores represent a greater number of devitalized cells, a condition associated with KCS. the overall scores for each eye were obtained by adding the scores over the four areas. Is there evidence of a difference between the two test preparations in the overall Rose-Bengal staining scores?

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A study enrolling 30  patients diasnosed with keratitis sicca (KCS) was conducted to determine the effect of a new ocular wetting agent, oker-rinse for improving ocular dryness based on rose-Bengal staining scored. patients were instructed to use oker-rinse in one eye and hypotears, as a control, in other eye 4 times a day for 3 weeks. Rose bengal staining scores were mesured as 0,1,2,3,or 4 in each of four areas of the eye: cornea, limbus, lateral conjunctiva and medical conjunctiva. higher scores represent a greater number of devitalized cells, a condition associated with KCS. the overall scores for each eye were obtained by adding the scores over the four areas. Is there evidence of a difference between the two test preparations in the overall Rose-Bengal staining scores?

Raw Data of Hypotears
and Oker -
Rinse
Patient Number
Нуpotears
Oker-Rinse
1
15
8
2
10
3
6
7
4
13
5
10
6
15
12
7
14
8
8
13
10
12
11
4
12
13
13
10
14
10
2
15
11
4
16
13
7
17
1
18
11
19
3
20
21
10
22
23
11
24
25
15
7.
26
2
27
28
8
8
29
8
12
30
Transcribed Image Text:Raw Data of Hypotears and Oker - Rinse Patient Number Нуpotears Oker-Rinse 1 15 8 2 10 3 6 7 4 13 5 10 6 15 12 7 14 8 8 13 10 12 11 4 12 13 13 10 14 10 2 15 11 4 16 13 7 17 1 18 11 19 3 20 21 10 22 23 11 24 25 15 7. 26 2 27 28 8 8 29 8 12 30
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