Answered: A recent study,1 compared 298 children…

MATLAB: An Introduction with Applications

6th Edition

ISBN:9781119256830

Author:Amos Gilat

Publisher:Amos Gilat

Chapter1: Starting With Matlab

Section: Chapter Questions

Problem 1P

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Chapter 6, Section 3-HT, Exercise 170 - MathPad

Autism and Maternal Antidepressant Use

A recent study,¹ compared 298 children with Autism Spectrum Disorder to 1507 randomly selected control children without the disorder. Of the children with autism, 20 of the mothers had used antidepressant drugs during the year before pregnancy or the first trimester of pregnancy. Of the control children, 50 of the mothers had used the drugs.

¹Croen, L., Grether, J., Yoshida, C., Odouli, R., and Hendrick, V., ‘‘Antidepressant Use During Pregnancy and Childhood Autism Spectrum Disorders,” Archives of General Psychiatry, 2011 Nov; 68(11): 1104-12.

(a) Is there a significant association between prenatal exposure to antidepressant medicine and the risk of autism? Test whether the results are significant at the 5% level.

State the null and alternative hypotheses. Your answer should be an expression composed of symbols: =,≠,<,>,μ,μ1,μ2,p,p1,p2,ρ,p^,p^1,p^2,r.

Use subscripts 1 for the children with autism and 2 for the control group.

H0: vs Ha:Edit

(b) Give the test statistic and the p-value.

Round your answer for the test statistic to two decimal places and your answer for the p-value to three decimal places.

test statistic = Enter your answer in accordance to item (b) of the question statement

p-value = Enter your answer in accordance to item (b) of the question statement

Reject H0.

Do not reject H0.

(d) Can we conclude that prenatal exposure to antidepressant medicine increases the risk of autism in the child?

Yes

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