A patient was being treated using an antibiotic, the plasma drug concentration was determined as 72.48 mg/L and 34.98 mg/L at 5.73 hours and 7.23 hours, respectively, following an IV bolus dose of the antibiotic. After three times the half life of the antibiotic, the patient was still displaying symptoms and thus it was decided to administer the antibiotic to the patient via constant rate infusion in order to maximize the therapeutic effect of the drug. How long did it take for the patient's plasma drug concentration to reach a steady state following the start of the constant rate infusion?
A patient was being treated using an antibiotic, the plasma drug concentration was determined as 72.48 mg/L and 34.98 mg/L at 5.73 hours and 7.23 hours, respectively, following an IV bolus dose of the antibiotic. After three times the half life of the antibiotic, the patient was still displaying symptoms and thus it was decided to administer the antibiotic to the patient via constant rate infusion in order to maximize the therapeutic effect of the drug. How long did it take for the patient's plasma drug concentration to reach a steady state following the start of the constant rate infusion?
Introduction to Chemical Engineering Thermodynamics
8th Edition
ISBN:9781259696527
Author:J.M. Smith Termodinamica en ingenieria quimica, Hendrick C Van Ness, Michael Abbott, Mark Swihart
Publisher:J.M. Smith Termodinamica en ingenieria quimica, Hendrick C Van Ness, Michael Abbott, Mark Swihart
Chapter1: Introduction
Section: Chapter Questions
Problem 1.1P
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A patient was being treated using an antibiotic, the plasma drug concentration was determined as 72.48 mg/L and 34.98 mg/L at 5.73 hours and 7.23 hours, respectively, following an IV bolus dose of the antibiotic. After three times the half life of the antibiotic, the patient was still displaying symptoms and thus it was decided to administer the antibiotic to the patient via constant rate infusion in order to maximize the therapeutic effect of the drug. How long did it take for the patient's plasma drug concentration to reach a steady state following the start of the constant rate infusion?
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