A particular allele is mice is lethal with homozygous genotype, however heterozygous mice develop normally. Why does this the lethal allele remain the population?
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- The rare recessive trait of albinism manifests as a lack of pigmentation in the skin. Albinism can be caused by mutations in any of several genes. A female mouse named Blanca exhibits albinism. She mated with two male mice, Ash and Whitey, and produced 3 offspring from each mating. • Ash exhibited albinism; all 3 of Blanca and Ash's offspring showed albinism. Whitey exhibited albinism; none of Blanca and Whitey's offspring showed albinism ● Determine the genotype for the offspring of Blanca and Ash. Capital letters denote wildtype alleles, and lower case letters denote mutant alleles. Mice are diploid. aaBB If Blanca and Ash had a fourth mouse in their litter, what is the probability that the fourth mouse will exhibit albinism? 1.0 Determine the most likely genotype for the offspring of Blanca and Whitey. Capital letters denote wildtype alleles, and lower case letters denote mutant alleles. Mice are diploid. AaBb If Blanca and Whitey had a fourth mouse in their litter, what is the…NLFN3, a gene in the X chromosome has been linked to Autism spectrum disorder ASD. Research has shown that the mutation R451C (represented by the allele X+) is recessive and causes ASD. Ear lobes in humans are coded by a single gene which displays simple dominance. E results in free earlobes, and e corresponds to attached earlobes. What is the probability of having a female offspring with ASD symptoms and attached earlobes from X+Y Ee and X+X ee parents? 25% O 100% 0% O 75% O 12.5% O 50%EXAMPLE PROBLEM Two black female mice are crossed with a brown male. In several litters, female I produced 9 black offspring and 7 brown; female II produced 57 black offspring. What deductions can you make about the inheritance of black and brown coat color in mice? What are the genotypes of the parents? Dominance and recessive describe which of two possible phenotypes are exhibited when two different alleles occur in the same individual.
- Sex determination in birds is different from that in humans. The sex chromosomes in birds are called Z and W, because males have two of the same chromosome (ZZ), whereas females have two different chromosomes (ZW). There is a Z-linked allele in some birds that causes the death of the embryo when the normal dominant allele is not present. What would be the sex ratio in the living offspring of a cross between a male heterozygous for the lethal allele and a normal female? A) What are the genotypes of the parents? Male____ Female____ B) Which gametes would each form? Male____ Female____ C) Draw your Punnett square below and determine the sex ratios of living offspring.In humans, Cystic Fibrosis an autosomal recessive trait, currently with medicine advances people affected by this disease can live until the 40s and 50s even. A couple in which the mother is a known carrier for this disease plans to have 4 children with a man who is not affected either but had his father who had the disease. A) Please state the genotypes of the parents. Use C to denote the dominant allele and c as the recessive B) Determine the probability that the first 2 children born have Cystic Fibrosis and the 2 last children are not affected. C) In general, what proportion of the children are expected to be female carriers of Cystic Fibrosis trait?Two brown bears have cubs in late spring. The mother bear has the phenotype for long front claws. The mother bear has the genotype (Aa), while the father has the same genotype as the mother. A) What percentage of the offspring will have long claws?
- In fruit flies, the dominant H allele gives rise to a hairless phenotype, hh gives rise to normal body bristles, and the HH homozygote condition is lethal during an embryonic stage. The presence of a dominant S allele suppresses the effect of the dominat H allele with respect to the body bristles phenotype such that normal body bristle phenotype is restored when only one dominant H allele is present (HH is lethal irrespective of the S or s alleles). The ss genotype has no effect over the H allele and the SS homozygote condition is also lethal during an embryonic stage. What would be the expected phenotypic outcomes among the surviving offspring from the following cross: HhSs X hhSs 2 normal body bristles: 1 hairless 7 normal body bristles: 2 hairless 1 normal body bristles: 1 hairless 3 normal body bristles: 1 hairless 5 normal body bristles: 1 hairlessIn chickens, a dominant hereditary abnormality (e.g., creepers) causes death when the genotype is homozygous (CC). The recessive condition (cc) at this locus produces a normal phenotype. Another gene locus with co dominant alleles is known to govern feather color such that the genotype FF = black, ff = splashed white, and Ff = blue. Also, a completely dominant gene W produces white skin. Yellow skin is produced by the homozygous genotype ww. QUESTIONS: In CcFfWw x ccffWw, what proportion of the offspring is: b.2 normal, white feathered, white skinned b.3 yellow skinnedIn cats, Manx (M) is a dominant allele that results in cats lacking a tail. The recessive allele (m) gives a cat with a tail. (A) Write out the genotype of a heterozygous cat (B) What is the phenotype of the cat in (A)? (C) The cat in (A) has offspring with a cat that has a tail. What fraction of the offspring of that cat will have tails? In peas, round (R) is dominant to wrinkled. (r )You cross a round pea plant to a wrinkled pea plant and half the offspring are round and half the offspring are wrinkled. What are the genotypes of the parents?
- You discover a new allele of a gene important for tail formation in mice. WT mice have long tails, but mice heterozygous for the allele have short tails. When you cross two heterozygous mice together, you obtain a 2:1 ratio of short-tailed mice to long-tailed mice. None of the short-tailed progeny are homozygous. What type of allele results in short tails? A) dominant negative allele B) temperature-sensitive allele C) lethal allele D) partially dominant allele E) incompletely penetrant alleleIn mice, gene A is epistatic to gene B. Dominant allele "A" allows for pigment to be transported to the fur; recessive allele "a" prevents the transport of pigment to the fur, resulting in an albino mouse. Dominant allele "B" gives agouti fur color; recessive allele "b" gives black fur color. What phenotype would you expect from a mouse with "aaBb" genotype? * A.black and white fur B.albino fur C. agouti fur D. black fur***18. Complete this flowchart to show how different alleles can result in different characteristics. In the DNA, different alleles of a gene have a different sequence of > different sequence of transcription > different sequence of in a protein translation > different structure and function of the protein (e.g. normal enzyme vs. defective enzyme) > different characteristics (e.g. normal color vs. albino) in