A method for the determination of the corticosteroid methylprednisolone acetate in solutions obtained from pharmaceutical preparations yielded a mean value of 3.7 mg mL with a standard deviation of 0.3 mg mL. For quality control purposes, the relative uncertainty in the concentration should be no more than 3%. How many samples of each batch should be analyzed to ensure that the relative standard deviation does not exceed 9% at the 95% confidence level? samples

A method for the determination of the corticosteroid methylprednisolone acetate in solutions obtained from pharmaceutical preparations yielded a mean value of 3.7 mg mL with a standard deviation of 0.3 mg mL. For quality control purposes, the relative uncertainty in the concentration should be no more than 3%. How many samples of each batch should be analyzed to ensure that the relative standard deviation does not exceed 9% at the 95% confidence level? samples

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

See similar textbooks

Related questions

Q: How do I find the standard deviation of the molaR CONCENTRATION and the relative standard deviation?…

A: A numerical problem based on standard deviation, which is to be accomplished.

Q: A new method was created to determine arsenic in rice. To validate this method, a reference standard…

A: Arsenic contamination in rice is a serious concern due to the potential health consequences.…

Q: How can I calculate this?

A: The given question is about analytical chemistry.

Q: The density of kerosene is 0.810 g/mL and was measured using a hydrometer with a standard deviation…

A: To propagate the error, we need to use the formula for the propagation of uncertainty: σV =…

Q: Molarity trail 1 0.0366 trail 2 0.0373 trail 3 0.0370 Calculate the standard deviation. Calculate…

Q: 5. If a clinical laboratory technician made 5 measurements of the same serum sample, and obtained…

Q: Analysis of several plant-food preparations for potassium ion yielded the following data: Sample…

A: A numerical problem based on general chemistry that is to be accomplished.

Q: You are measuring the isooctane concentration in a hydrocarbon mixture with a chromatographic…

A: Plot the calibration curve by plotting isooctane concentration on x-axis and peak area on y-axis.

Q: A group of students titrate a calcium carbonate standard solution repeatedly in five experimental…

A: Average concentration = 80.5 ppm Standard deviation = 0.5 ppm Confidence interval = 95% Number of…

Q: AA (mg/g) UV (ug/ml) Sample (ug/ml) Unknown Fe solution 1 Unknown Fe solution _2 0.322 8.136 0.318…

A: Mean, standard deviations, confidence limit are calculated using respective formulas. We can't use…

Q: A biosensor was developed to measure the concentration of aqueous arsenic. To determine the accuracy…

A: Confidence interval is used to measure the accuracy of the biosensor.The test is to determine the…

Q: A method for the detection of morphine is used to generate a calibration curve in which the assay…

A: The explanation is given below-

Q: The determination of copper in a sca water sample gave a mean value of 77.81 ug/L and a standard…

Q: Question 8 (Mandatory) ( Calculate the mean and standard deviation for the results below for the…

A: The concentration of lead in a soil sample.23.2 ppm, 20.1 ppm, 24.7 ppm, 19.9 ppm, 21.8 ppmmean and…

Q: Calculate the mean and sample standard deviation for the following data: 90.0, 90.0, 85.0, 83.0,…

A: The mean or average of the sample is obtained by dividing the sum of the given measurements by the…

Q: A chemical synthesis was carried out four times, resulting in yields of 51.2%,51.2%, 57.4%,57.4%,…

Q: For a concentration technique, Stotal is given as 19.31 ± 0.035, Smb is 0.22 ± 0.008, and kA is…

A: We will choose the false statement answer for the above question.

Q: 3-3 Types of Error; 3-4 Propagation of Uncertainty from Random Error (30 min) If A = 3.475 (+0.002),…

Q: A method to determine an antibiotic was developed and validated in a pharmaceutical company. The…

A: In the given question, calculate the number of samples to be analyzed to ensure that the antibiotic…

Q: What is the relative average deviation in the following percent KHP values in ppt? (Enter your…

A: The relative average deviation is a measure of the average deviation relative to the average value.…

Q: Question: Using a method for the determination of % CaO in limestone the following results were…

A: There are numerous molecules in inorganic chemistry. Every molecule has molecular formula as well as…

Q: Calculate the sample standard deviation, s, for this set of data: 5.2, 7.8, 8.6, 9.6, 2.0, 8.7

A: Here we are required to find the standard deviation for the given set of data.

Question

[References)
A method for the determination of the corticosteroid methylprednisolone acetate in solutions obtained from pharmaceutical preparations yielded a mean
value of 3.7 mg mL with a standard deviation of 0.3 mg mL. For quality control purposes, the relative uncertainty in the concentration should be
no more than 3%. How many samples of each batch should be analyzed to ensure that the relative standard deviation does not exceed 9% at the 95%
confidence level?
samples

Expert Solution

This question has been solved!

Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.

This is a popular solution!

SEE SOLUTION Check out a sample Q&A here

Step 1

VIEW

Step 2

VIEW

Trending now

This is a popular solution!

Step by step

Solved in 2 steps

SEE SOLUTION Check out a sample Q&A here

Knowledge Booster

Learn more about

Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.

Similar questions

Calculate the mean and sample standard deviation for the following data: 90.0, 90.0, 85.0, 83.0, 80.0, 78.0, 77.0, 75.0, 70.0. Group of answer choices 79.8 ±± 5.83 79.8 ±± 6.23 80.9 ±± 6.75 80.9 ±± 6.37
A technician determines the concentration of calcium in milk using two instrumental methods. If Fcalculated > Ftable for the two sets of calcium data, what conclusion(s) can the technician make? I. The difference in standard deviations for the two instrumental methods is significant. II. The difference in standard deviations for the two instrumental methods is not significant. III. The data come from populations with the same standard deviation. IV. The data do not come from populations with the same standard deviation. II and III II I and IV I and III O II and IV
How to calculate?
Measurements of boiling temperatures of samples of a liquid (°C) are given below: 78.4 79.0 78.8 79.2 78.6 Calculate the meanCalculate the modeCalculate the standard deviation
Titration of an oxalate sample gave the following percentages: 15.07 % , 15.58 % , and 15.42 % . Calculate the average. Calculate the standard deviation.
A young researcher was evaluating a standard method for determining the methylmercury content in blue fin tuna using high performance liquid chromatography (HPLC). She determined the standard deviation (?)(s) for the method to be 0.440.44 ppb and assumed that ?s was a good approximation of ?σ . As a test, she used this method to evaluate the methylmercury content in a National Institutes of Standards and Technology (NIST) standard and determined the unknown amount to be within 0.210.21 ppb (?)(μ) of the known mean with 99% probability. How many replicate measurements of the NIST standard did the researcher perform?
Suppose a certain species of fawns between 1 and 5 months old have a body weight that is approximately normally distributed with mean μ=28.6 kilograms and standard deviation σ=3.7 kilograms. Let x be the weight of a fawn in kilograms. Convert the following z interval to a x interval. 2.7 < z Choices x < 18.61 x < 38.59 x > 38.59 x > 18.61 x -38.59
Solve both parts otherwise I will downvote
A student determines the concentration of an unknown sample using two different methods. Each method has three different trials; the average, standard deviation and percent error produced by each method is listed below. Method 1 Average: 10.56 M NaOH Standard deviation: 1.35 M NaOH Percent error: 1.25% Method 2 Average: 10.92 M NaOH Standard deviation: 1.02 M NaOH Percent error: 3.45% Which method was more precise? How can you tell?
The following volumes were obtained for the calibration of a 10 - mL pipet: 10.028415, 10.140035, 10.091111, and 10.012213 mL. Calculate the mean value, the standard deviation and then report your value.
To test the quality of the work of a commercial laboratory, duplicate analyses of apurified benzoic acid (68.8% C, 4.953% H) sample were requested. It is assumed that therelative standard deviation of the method is sr →  = 4 ppt for carbon and 6 ppt forhydrogen. The means of the reported results are 68.5% C and 4.882% H. At the 95%confidence level, is there any indication of systematic error in either analysis?
Find the result (c) and the absolute standard deviation (sc) as propagated in the following calculation. Express final result and its propagated standard deviation with an appropriate number of significant figures. a = 5.75 (+0.05)+0.833 (±0.001); b = 3.75 (±0.02);c = alb