A hypothetical neuronal cell shows the following intracellular and extracellular concentration of sodium, potassium, calcium, and chloride ions.   Extracellular concentration (mM) Intracellular concentration (mM) (Ion)out/ (Ion)inside E ion at 37 oC Sodium ion 420 60     Potassium ion 25 420     Calcium ion 16 0.4     Chloride 565 45       Calculate the Nernst potential of these ions at 37 oC . Show your work.

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Chapter1: Chemical Foundations
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A hypothetical neuronal cell shows the following intracellular and extracellular concentration of sodium, potassium, calcium, and chloride ions.

 

Extracellular concentration (mM)

Intracellular concentration (mM)

(Ion)out/ (Ion)inside

E ion at 37 oC

Sodium ion

420

60

 

 

Potassium ion

25

420

 

 

Calcium ion

16

0.4

 

 

Chloride

565

45

 

 

 

  1. Calculate the Nernst potential of these ions at 37 oC . Show your work. 
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The Nernst equation is that equation which can be used to evaluate the electrode potential at any conditions of pressure, temperature and the concentration for an electrode.

The mathematical formula that can be applied to evaluate the Nernst potential for an ion is;

Eion=2.303RTFZlogionoutioninHere,Eion=Potential of a particular ion R=Gas constantF=Faraday's constantZ=Charge on particular ion

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