a) Compound 1 is the precursor of a class of compounds with antibacterial properties. Knowing that the pyrrole core is synthesised via Paal-Knorr synthesis, propose the structure of the di-carbonyl (2) and amine (3) fragments that take part in the reaction : CI G N CH3 CI →>> H 2 b) The last step of the synthetic pathway involves the reaction of compound 4 with amine 5. Draw the structure of product 6. CH3 NH₂ 5 3 CH₂COOH cat.
a) Compound 1 is the precursor of a class of compounds with antibacterial properties. Knowing that the pyrrole core is synthesised via Paal-Knorr synthesis, propose the structure of the di-carbonyl (2) and amine (3) fragments that take part in the reaction : CI G N CH3 CI →>> H 2 b) The last step of the synthetic pathway involves the reaction of compound 4 with amine 5. Draw the structure of product 6. CH3 NH₂ 5 3 CH₂COOH cat.
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Transcribed Image Text:a) Compound 1 is the precursor of a class of compounds with antibacterial
properties. Knowing that the pyrrole core is synthesised via Paal-Knorr
synthesis, propose the structure of the di-carbonyl (2) and amine (3)
fragments that take part in the reaction :
o
CI
CH3
2
CH3
b) The last step of the synthetic pathway involves the reaction of compound 4
with amine 5. Draw the structure of product 6.
NH₂
5
3
CH₂COOH cat.
Answered: a) Compound 1 is the precursor of a...
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