A clinical trial is planned to compare an experimental medication designed to lower blood pressure to a placebo. Before starting the trial, a pilot study is conducted involving seven participants. The objective of the study is to assess how systolic blood pressure (SBP) changes over time if left untreated. SBP is measured at baseline and again 4 weeks later. Is there a statistically significant difference in SBP over time? Run the test at a 5% level of significance. Baseline 120 145 130 160 152 143 126 Four weeks 122 142 135 158 155 140 130   (Use Excel)

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2-Proportion Test

In a 2-proportion test, two separate proportions are measured at the same time, and their similarity is evaluated. It is also known as a 2-proportion z-test, and a comparison of two different proportions is done in this method.