A 3-month-old female is hospitalized with a variety of health problems consistent with severe inflammation affecting multiple tissues. Laboratory tests reveal that the patient lacks a cell population with the following phenotype: CD4+, CD25*, FoxP3*. The patient most likely suffers from a deficiency in a cell type that regulates T cell activation by which of the following mechanisms? a. Induction of receptor editing b. Secretion of IL-3 c. Induction of dendritic cell maturation d. Consumption of IL-2 Oe. Induction of thymic involution

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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A 3-month-old female is hospitalized with a variety of health problems consistent with severe inflammation
affecting multiple tissues. Laboratory tests reveal that the patient lacks a cell population with the following
phenotype: CD4+, CD25*, FoxP3+. The patient most likely suffers from a deficiency in a cell type that regulates T
cell activation by which of the following mechanisms?
O
a. Induction of receptor editing
b. Secretion of IL-3
c. Induction of dendritic cell maturation
d. Consumption of IL-2
e. Induction of thymic involution
Clear my choice
Transcribed Image Text:A 3-month-old female is hospitalized with a variety of health problems consistent with severe inflammation affecting multiple tissues. Laboratory tests reveal that the patient lacks a cell population with the following phenotype: CD4+, CD25*, FoxP3+. The patient most likely suffers from a deficiency in a cell type that regulates T cell activation by which of the following mechanisms? O a. Induction of receptor editing b. Secretion of IL-3 c. Induction of dendritic cell maturation d. Consumption of IL-2 e. Induction of thymic involution Clear my choice
A 24-year-old male with a history of eating undercooked chicken reports to the clinic with gastrointestinal
distress. He is promptly diagnosed with bacterial Salmonellosis. Salmonella species invade the intestinal
epithelium via which one of the following cell types, which normally functions to transport organisms and particles
from the gut lumen to immune cells in the lymphoid tissue of the lamina propria?
a. Paneth cells
Ob. Goblet cells
Oc. Tuft cells
d. Microfold (M) cells
Oe. Intraepithelial lymphocytes
Clear my choice
Transcribed Image Text:A 24-year-old male with a history of eating undercooked chicken reports to the clinic with gastrointestinal distress. He is promptly diagnosed with bacterial Salmonellosis. Salmonella species invade the intestinal epithelium via which one of the following cell types, which normally functions to transport organisms and particles from the gut lumen to immune cells in the lymphoid tissue of the lamina propria? a. Paneth cells Ob. Goblet cells Oc. Tuft cells d. Microfold (M) cells Oe. Intraepithelial lymphocytes Clear my choice
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