A 0.2985 g sample of an antibiotic powder was dissolved in HCl and the solution diluted to 100.0 mL. A 20.00 ml aliquot was transferred to a flask and followed by 25.00 ml of 0.01886 M KBRO3. An excess of KBr was added to form Br2, and the flask was stoppered. After 10 min, during which time the Br2 brominated the sulfanilamide, an excess of KI was added. The liberated iodine titrated with 12.88 ml of 0.1235 M sodium thiosulfate. Calculate the percent sulfanilamide (NH2C,H4SO2NH2) in the powder. Bro, + 5Br + 6H* 3Br, + 3H,0 NH2 NH2 Br. Br + 2B12 + 2H++ 2Br SO,NH2 SO,NH2 sulfanilamide Br, + 51 2Br + 12 excess 2 + 25,0,- 25,0,2 + 21- - MM: NH2C6H4SO2NH2 = 172.21 KBRO3 = 167.00 KBr 119.00

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A 0.2985 g sample of an antibiotic powder was dissolved in HCl and the solution diluted to 100.0 mL. A
20.00 ml aliquot was transferred to a flask and followed by 25.00 ml of 0.01886 M KBRO3. An excess of
KBr was added to form Br2, and the flask was stoppered. After 10 min, during which time the Br2
brominated the sulfanilamide, an excess of KI was added. The liberated iodine titrated with 12.88 ml of
0.1235 M sodium thiosulfate. Calculate the percent sulfanilamide (NH2C,H4SO2NH2) in the powder.
Bro, + 5Br + 6H*
3Br, + 3H,0
NH2
NH2
Br.
Br
+ 2B12
+ 2H++ 2Br
SO,NH2
SO,NH2
sulfanilamide
Br, + 51
2Br + 12
excess
2 + 25,0,-
25,0,2 + 21-
-
MM: NH2C6H4SO2NH2 = 172.21
KBRO3
= 167.00
KBr
119.00
Transcribed Image Text:A 0.2985 g sample of an antibiotic powder was dissolved in HCl and the solution diluted to 100.0 mL. A 20.00 ml aliquot was transferred to a flask and followed by 25.00 ml of 0.01886 M KBRO3. An excess of KBr was added to form Br2, and the flask was stoppered. After 10 min, during which time the Br2 brominated the sulfanilamide, an excess of KI was added. The liberated iodine titrated with 12.88 ml of 0.1235 M sodium thiosulfate. Calculate the percent sulfanilamide (NH2C,H4SO2NH2) in the powder. Bro, + 5Br + 6H* 3Br, + 3H,0 NH2 NH2 Br. Br + 2B12 + 2H++ 2Br SO,NH2 SO,NH2 sulfanilamide Br, + 51 2Br + 12 excess 2 + 25,0,- 25,0,2 + 21- - MM: NH2C6H4SO2NH2 = 172.21 KBRO3 = 167.00 KBr 119.00
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