8. Provide and resonance explanation as to why bromination (Br,/FeBr,) of acetophenone occurs meta compared to bromination of anisole, which occurs para. For simplicity, go ahead and use "Br" as the electrophile. Draw the mechanism for the reaction and resonance structures of the Substrate before the reaction occurs. fi دے رے olp ده on Ew & attached -> less rucheephilic are رے 22

8. Provide and resonance explanation as to why bromination (Br,/FeBr,) of acetophenone occurs meta compared to bromination of anisole, which occurs para. For simplicity, go ahead and use "Br" as the electrophile. Draw the mechanism for the reaction and resonance structures of the Substrate before the reaction occurs. fi دے رے olp ده on Ew & attached -> less rucheephilic are رے 22

Organic Chemistry

8th Edition

ISBN:9781305580350

Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Chapter11: Ethers, Epoxides, And Sulfides

Section: Chapter Questions

Problem 11.42P

See similar textbooks

Similar questions

Consider reaction 1 and reaction 2 shown below. Reaction 1 Reaction 2 CH,CH AICI, CH₂COCI AlCl3, H₂O dimethylated benzenes and other products a) Both reaction 1 and reaction 2 proceed via a similar mechanism. Name the type of mechanism undergone b) Suggest why substituted benzene from reaction 1 gives a mixture of organic products while substituted benzene from reaction 2 gives only one mono-substituted product. c) The organic product in reaction 2, acetophenone, produce the corresponding cyanohydrin under certain experimental conditions. (i) State the reagents and conditions involved. (ii) Name the type of mechanism undergone. (iii) Predict and draw the product of corresponding cyanohydrin. d) State the importance of cyanohydrin.
Which position will an electophile (E*) most likely add in an Electophilic Aromatic Substitution (EAS) reaction? C A
Write a reasonable mechanism for the following transformation.
Although codeine occurs in low concentration in the opium poppy, most of the codeine used in medicine is prepared from morphine (the principal component of opium) by the following reaction. Explain why selective methylation occurs at only one OH in morphine to give codeine. Codeine is a less potent and less addictive analgesic than morphine. но. CH,0. [1 кон H [2] CH3I H. CH3 H Ho morphine H. CH3 Ho codeine
In the reaction of a nitrile with a Grignard reagent, there are two steps: a) nucleophilic addition of the Grignard to form an imine ion and b) hydrolysis of the imine to form a ketone. Draw the intermediate and the final product in this reaction. Ignore inorganic byproducts. 1. CH₂MgBr 2. H3O* Draw Imine Ion Intermediate 1. H30¹ 2. Neutralizing work-up a
Provide a plausible arrow pushing mechanism for the reaction below. CI 8.00 2 eq H20
20:33 1 : ●●● all the proper notations for depicting resonance. 4. Provide the full mechanism (curved arrows and intermediates) that leads to the product in the scheme below. Draw the structure of the product to help you see how the starting materials will combine. Use that as a clue to figure out how to draw the mechanism arrows. ccare in your scheme. Be sure to use NaOEt 00 i 5. Provide the major organic product of the reaction shown. Determine if these conditions are best for SN2, SN1, E2, or E1. Be sure to indicate stereochemistry by using the proper wedges/dashes in the product. acetone phenyl butanoate Send a chat O
CHEM 2252 Label the following compounds as aromatic, anti-aromatic, or non-aromatic (assume that all molecules are planar). In-class Assignment #4 Predict the product that would be formed when biphenyl reacts with a mixture of nitric and sulfuric acid. Draw a detailed, step-wise mechanism that shows formation of the electrophile and explains the observed regiochemistry. HNO3 H₂SO4
H9.27 - Level 1 X Answered - Incorrect • 1 attempt left The conversion of compound A to compound E in the previous question occurs via three intermediates (compounds B-D) and a series of different mechanisms. Sort the reaction mechanisms below in order of occurrence during the conversion of compound A into Compound E. X Loss of a leaving group X Rearrangement X Proton transfer X Your answer H2SO4 compound A compound E
3
I need help please
Show how the enamine below can be synthesized. Then draw the resonance structure(s) for the enamine. 그