8. Organometallic reagents, such as organolithium (RLi), Gilman or Organo-cuprates (R2)CuLi) and Grignard (R MgBr), have been known to transform ketones and aldehyde molecules. Pages 1032-1033 show these reagents can modify acid chlorides, acid anhydrides and esters. OR Given the reactions below, provide the missing products, indicate the likely intermediates and explain all routes yield a alcohol. ÇI 1. LİCH3, ether, rt 2. H;O* 1. CH,CH,MgBr, diethyl ether 2. НС, Н,О 1. (PHCH2),CuLi, THF Ph 2. HCС, Н,О

8. Organometallic reagents, such as organolithium (RLi), Gilman or Organo-cuprates (R2)CuLi) and Grignard (R MgBr), have been known to transform ketones and aldehyde molecules. Pages 1032-1033 show these reagents can modify acid chlorides, acid anhydrides and esters. OR Given the reactions below, provide the missing products, indicate the likely intermediates and explain all routes yield a alcohol. ÇI 1. LİCH3, ether, rt 2. H;O* 1. CH,CH,MgBr, diethyl ether 2. НС, Н,О 1. (PHCH2),CuLi, THF Ph 2. HCС, Н,О

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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3. If your product from this experiment (benzimidazole) is treated with a strong base (nBuLi) followed by benzyl bromide (Ph-CH2-Br) in a polar aprotic solvent like DMSO, a molecule C4H12N, is formed. Please draw a reaction scheme of the overall sequence (including the structure of the product), and also an electron-pushing mechanism for each of the reactions that take place.
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