8. Identify the inhibitor from the following list for the selective target of the enzyme having C in the sequence of 7651 TOLMPFG CTS LL DY VREH781 Explain for the reason of selectivity. HN HN Br Br HN Br N. N. MeO. N. N. N' N. H. N' MeO What type of inhibitor of Imatinib is ? Identify the H-bonding site with the hinge region and the other binding interaction(s) with the kinase. .N. N. N. "Me Imatinib Me
8. Identify the inhibitor from the following list for the selective target of the enzyme having C in the sequence of 7651 TOLMPFG CTS LL DY VREH781 Explain for the reason of selectivity. HN HN Br Br HN Br N. N. MeO. N. N. N' N. H. N' MeO What type of inhibitor of Imatinib is ? Identify the H-bonding site with the hinge region and the other binding interaction(s) with the kinase. .N. N. N. "Me Imatinib Me
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Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
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Transcribed Image Text:8. Identify the inhibitor from the following list for the selective target of the
having C73 in the sequence of 7651 TOLMPFG C773 LL D Y VREH781
Explain for the reason of selectivity.
enzyme
HN
HN
Br
Br
HN
Br
MeO.
MeO
1
What type of inhibitor of Imatinib is ? Identify the H-bonding site with the hinge
region and the other binding interaction(s) with the kinase.
Imatinib
Me
Me
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