7. The addition of organometallic compounds to carbonyls is one of the reactions of great interest for the synthesis of pharmaceutical products, an important case is the sequence of reactions used for the formation of the drug viprostol, used in topical forms for the treatment of peripheral vascular conditions. Complete the synthesis route of viprostol and perform the reaction mechanism to obtain

Organic Chemistry
9th Edition
ISBN:9781305080485
Author:John E. McMurry
Publisher:John E. McMurry
Chapter23: Carbonyl Condensation Reactions
Section23.SE: Something Extra
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7. The addition of organometallic compounds to carbonyls is one of the reactions of great interest
for the synthesis of pharmaceutical products, an important case is the sequence of reactions used
for the formation of the drug viprostol, used in topical forms for the treatment of peripheral vascular
conditions. Complete the synthesis route of viprostol and perform the reaction mechanism to obtain
В.
Viprostol
1.
Cro,
1.
он
R1 = n-pentil
2.
2.
R2
What product will be obtained if hydrobromic acid is added to product B? Draw the structure and
reaction mechanism.
Transcribed Image Text:7. The addition of organometallic compounds to carbonyls is one of the reactions of great interest for the synthesis of pharmaceutical products, an important case is the sequence of reactions used for the formation of the drug viprostol, used in topical forms for the treatment of peripheral vascular conditions. Complete the synthesis route of viprostol and perform the reaction mechanism to obtain В. Viprostol 1. Cro, 1. он R1 = n-pentil 2. 2. R2 What product will be obtained if hydrobromic acid is added to product B? Draw the structure and reaction mechanism.
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