7. How could you perform the following transformation? Br ?

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Q: ОН 1. mCPBA 2. Н3О+ ОН О

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Q: 1. Provide the missing product, reagent, or starting material for each reaction. CH;CH2ONA

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Q: 7. How could you perform the following transformation? Br

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Q: eactivity? Does it just mean the ring cannot undergo a ring flip LIAIH4 tBu

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Q: 2) Draw all products formed in the following SN1 reaction. Br CH;CH2OH

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Q: NABH4 MeOH OH LAH THE

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Q: Identify the reagent that should be used to complete the transformation shown below. 1. BH(CH11)2 2.…

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Q: H9SO4 H2SO4, H2O tautomerization ОН Figure 15: Reactions

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Reactions at the Alpha Carbon Atom

The position next to the ketone or aldehyde functional group is termed as alpha position and the reaction which occurs at alpha position is called alpha substitution reaction. In an alpha substitution reaction, the alpha proton atom is substituted by an electrophile by the formation of an enol intermediate or enolate ion intermediate. Most of the carbonyl compounds go through an alpha substitution reaction.