7. DNA synthesis Suppose that upon synthesizing a molecule of DNA, you introduce a wrong base pair, on average, every 1000 base pairs. Suppose you synthesize a DNA molecule that is 1000 bases long. (a) Calculate and draw a bar graph indicating the yield (probability) of each product DNA, containing 0, 1, 2, and 3 mutations (wrong base pairs). (b) Calculate how many combinations of DNA sequences of 1000 base pairs contain exactly 2 mutant base pairs. (c) What is the probability of having specifically the 500th base pair and the 888th base pair mutated in the pool of DNA that has only two mutations? (d) What is the probability of having two mutations side-by-side in the pool of DNA that has only two mutations?

MATLAB: An Introduction with Applications
6th Edition
ISBN:9781119256830
Author:Amos Gilat
Publisher:Amos Gilat
Chapter1: Starting With Matlab
Section: Chapter Questions
Problem 1P
icon
Related questions
Question
27. DNA synthesis Suppose that upon synthesizing a molecule of DNA, you introduce a wrong base pair, on average, every 1000 base pairs. Suppose you synthesize a DNA molecule that is 1000 bases long.
(a) Calculate and draw a bar graph indicating the yield (probability) of each product DNA, containing 0, 1, 2, and 3 mutations (wrong base pairs).
(b) Calculate how many combinations of DNA sequences of 1000 base pairs contain exactly 2 mutant base pairs.
(c) What is the probability of having specifically the 500th base pair and the 888th base pair mutated in the pool of DNA that has only two mutations?
(d) What is the probability of having two mutations side-by-side in the pool of DNA that has only two mutations?
Transcribed Image Text:27. DNA synthesis Suppose that upon synthesizing a molecule of DNA, you introduce a wrong base pair, on average, every 1000 base pairs. Suppose you synthesize a DNA molecule that is 1000 bases long. (a) Calculate and draw a bar graph indicating the yield (probability) of each product DNA, containing 0, 1, 2, and 3 mutations (wrong base pairs). (b) Calculate how many combinations of DNA sequences of 1000 base pairs contain exactly 2 mutant base pairs. (c) What is the probability of having specifically the 500th base pair and the 888th base pair mutated in the pool of DNA that has only two mutations? (d) What is the probability of having two mutations side-by-side in the pool of DNA that has only two mutations?
Expert Solution
trending now

Trending now

This is a popular solution!

steps

Step by step

Solved in 5 steps with 12 images

Blurred answer
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
MATLAB: An Introduction with Applications
MATLAB: An Introduction with Applications
Statistics
ISBN:
9781119256830
Author:
Amos Gilat
Publisher:
John Wiley & Sons Inc
Probability and Statistics for Engineering and th…
Probability and Statistics for Engineering and th…
Statistics
ISBN:
9781305251809
Author:
Jay L. Devore
Publisher:
Cengage Learning
Statistics for The Behavioral Sciences (MindTap C…
Statistics for The Behavioral Sciences (MindTap C…
Statistics
ISBN:
9781305504912
Author:
Frederick J Gravetter, Larry B. Wallnau
Publisher:
Cengage Learning
Elementary Statistics: Picturing the World (7th E…
Elementary Statistics: Picturing the World (7th E…
Statistics
ISBN:
9780134683416
Author:
Ron Larson, Betsy Farber
Publisher:
PEARSON
The Basic Practice of Statistics
The Basic Practice of Statistics
Statistics
ISBN:
9781319042578
Author:
David S. Moore, William I. Notz, Michael A. Fligner
Publisher:
W. H. Freeman
Introduction to the Practice of Statistics
Introduction to the Practice of Statistics
Statistics
ISBN:
9781319013387
Author:
David S. Moore, George P. McCabe, Bruce A. Craig
Publisher:
W. H. Freeman