7. Determine the net charge at pH 6 on each peptide shown below. The pKa's of relevant side chain functionality are given. The pKa of the NH groups within the backbones of the rings is about 20. pK₂= 10 HO NH3 pka = 11 -NH pK₂=4 HO- NH NH -NH HN HN HN SH pk₂ = 8 Net charge:

Organic Chemistry
9th Edition
ISBN:9781305080485
Author:John E. McMurry
Publisher:John E. McMurry
Chapter26: Biomolecules: Amino Acids, Peptides, And Proteins
Section26.1: Structures Of Amino Acids
Problem 1P: How many of the -amino acids shown in Table 26-1 contain aromatic rings? How many contain sulfur?...
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7. Determine the net charge at pH 6 on each peptide shown below. The pKa's of relevant side chain
functionality are given. The pKa of the NH groups within the backbones of the rings is about 20.
pK₂= 10 HO
NH3 pk₂ = 11
-NH
pK₂=4 HO-
NH
NH
-NH
HN
HN
HN
SH pk₂ = 8
Net charge:
Transcribed Image Text:7. Determine the net charge at pH 6 on each peptide shown below. The pKa's of relevant side chain functionality are given. The pKa of the NH groups within the backbones of the rings is about 20. pK₂= 10 HO NH3 pk₂ = 11 -NH pK₂=4 HO- NH NH -NH HN HN HN SH pk₂ = 8 Net charge:
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