7. Describe the mutation that causes sickle cell anemia. a. What is the change that occurs in DNA? b. What is the amino acid change that happen? Is it a conservative (similar amino acid) change or not? C. What is the change in tertiary structure? d. What is the change in quaternary structure? e. How is it possible that such a (small) change causes such an extreme effect?

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
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Chapter1: The Human Body: An Orientation
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**Sickle Cell Anemia Mutation Overview**

1. **Describe the mutation that causes sickle cell anemia.**

   a. **What is the change that occurs in DNA?**

   b. **What is the amino acid change that happens? Is it a conservative (similar amino acid) change or not?**

   c. **What is the change in tertiary structure?**

   d. **What is the change in quaternary structure?**

   e. **How is it possible that such a (small) change causes such an extreme effect?**
Transcribed Image Text:**Sickle Cell Anemia Mutation Overview** 1. **Describe the mutation that causes sickle cell anemia.** a. **What is the change that occurs in DNA?** b. **What is the amino acid change that happens? Is it a conservative (similar amino acid) change or not?** c. **What is the change in tertiary structure?** d. **What is the change in quaternary structure?** e. **How is it possible that such a (small) change causes such an extreme effect?**
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