7. A local ophthalmologist is treating one of his patients for a post-LASIK eye infection that is notresponding to topical ciprofloxacin. These infections, although rare, can occur after laser in situkeratomileusis (LASIK) surgery for vision correction. The ophthalmologist prescribes 60 ml of a 2.5%amikacin sulfate isotonic solution, 2 drops in the affected eye every 2 hours.Amikacin sulfate USP (C22H43N;O13•2H,SO4), m.w., 781.76, is an aminoglycoside-type antibioticcontaining 3-ions.a) Determine the weight in grams of amikacin sulfate needed to prepare the solution.b) Calculate the sodium chloride equivalent (E value) for amikacin sulfate.c) Calculate the amount of sodium chloride needed to make the prepared solution isotonic.d) How many milliliters of 23.5% sodium chloride should be used to obtain the needed sodiumchloride?

Given: Volume of solution = 60 mL % of Amikacin sulfate in solution = 2.5 % molar mass of Amikacin…

7. A local ophthalmologist is treating one of his patients for a post-LASIK eye infection that is not responding to topical ciprofloxacin. These infections, although rare, can occur after laser in situ keratomileusis (LASIK) surgery for vision correction. The ophthalmologist prescribes 60 ml of a 2.5% amikacin sulfate isotonic solution, 2 drops in the affected eye every 2 hours. Amikacin sulfate USP (C22H43N;O13•2H2SO4), m.w., 781.76, is an aminoglycoside-type antibiotic containing 3-ions. a) Determine the weight in grams of amikacin sulfate needed to prepare the solution. b) Calculate the sodium chloride equivalent (E value) for amikacin sulfate. c) Calculate the amount of sodium chloride needed to make the prepared solution isotonic. d) How many milliliters of 23.5% sodium chloride should be used to obtain the needed sodium chloride?

7. A local ophthalmologist is treating one of his patients for a post-LASIK eye infection that is not responding to topical ciprofloxacin. These infections, although rare, can occur after laser in situ keratomileusis (LASIK) surgery for vision correction. The ophthalmologist prescribes 60 ml of a 2.5% amikacin sulfate isotonic solution, 2 drops in the affected eye every 2 hours. Amikacin sulfate USP (C22H43N;O13•2H2SO4), m.w., 781.76, is an aminoglycoside-type antibiotic containing 3-ions. a) Determine the weight in grams of amikacin sulfate needed to prepare the solution. b) Calculate the sodium chloride equivalent (E value) for amikacin sulfate. c) Calculate the amount of sodium chloride needed to make the prepared solution isotonic. d) How many milliliters of 23.5% sodium chloride should be used to obtain the needed sodium chloride?

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter11: Properties Of Solutions

Section: Chapter Questions

Problem 117AE: Patients undergoing an upper gastrointestinal tract laboratory test are typically given an X-ray...

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Concept explainers

Solutions

Solutions can be considered as homogeneous mixtures which contain two or more than two chemical substances. The chemical substance which is the greater part is defined as solvent. And the chemical substance that is dissolved in a solvent is referred to as solute. Solution chemistry plays an important role in chemistry since it supports many commercial applications of solutions.

Question

7. A local ophthalmologist is treating one of his patients for a post-LASIK eye infection that is not
responding to topical ciprofloxacin. These infections, although rare, can occur after laser in situ
keratomileusis (LASIK) surgery for vision correction. The ophthalmologist prescribes 60 ml of a 2.5%
amikacin sulfate isotonic solution, 2 drops in the affected eye every 2 hours.
Amikacin sulfate USP (C22H43N;O13•2H,SO4), m.w., 781.76, is an aminoglycoside-type antibiotic
containing 3-ions.
a) Determine the weight in grams of amikacin sulfate needed to prepare the solution.
b) Calculate the sodium chloride equivalent (E value) for amikacin sulfate.
c) Calculate the amount of sodium chloride needed to make the prepared solution isotonic.
d) How many milliliters of 23.5% sodium chloride should be used to obtain the needed sodium
chloride?

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