6. A runner just finished a marathon. (a) Which hormone is being secreted to the blood: insulin or glucagon? From which organ and cell t (b) What is the secondary messenger (a small molecule) important for the signaling of the horme

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
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For question C, i need help on parts d,e, and f 

### Question 6: Post-Marathon Biochemical Analysis

**Context:** A runner just finished a marathon.

---

#### (a) Which hormone is being secreted into the blood: insulin or glucagon? From which organ and cell type?

**Answer:**
- **Hormone:** (Answer pending)
- **Organ:** (Answer pending)
- **Cell Type:** (Answer pending)

---

#### (b) What is the secondary messenger (a small molecule) important for the signaling of the hormone?

**Answer:** (Answer pending)

---

#### (c) For the enzymes listed below, indicate whether the enzyme activity is upregulated (↑) or downregulated (↓) in the muscle and liver, respectively.

**Table of Enzyme Regulation:**

| Enzyme                         | Muscle | Liver |
|--------------------------------|--------|-------|
| (a) Glycogen synthase          |        |       |
| (b) Phosphofructokinase-1      |        |       |
| (c) Fructose-Bisphosphatase-2  |        |       |
| (d) Pyruvate kinase            |        |       |
| (e) Pyruvate carboxylase       |        |       |
| (f) Acetyl-CoA carboxylase     |        |       |

**Note:** The fill-in for regulation status (↑ or ↓) should be provided based on the knowledge of metabolic responses post-exercise, which is not indicated in the provided text.

---

### Explanation of Graphs or Diagrams

There are no graphs or diagrams in the provided image.

---

#### Educational Context

This exercise is designed to evaluate understanding of metabolic and hormonal regulation in response to endurance exercise such as a marathon. It touches on key biochemical principles including hormone signaling and enzyme regulation.

Students should be able to:
1. Identify which hormone (insulin or glucagon) would dominate in a post-marathon scenario and understand its origin and the type of cells secreting it.
2. Understand the role and identity of secondary messengers in hormone signaling.
3. Deduce the regulatory response (upregulation or downregulation) of key metabolic enzymes in muscle and liver tissues post-exercise. 

Students are encouraged to review the metabolic pathways and hormone signaling mechanisms to accurately complete the table and answers.
Transcribed Image Text:### Question 6: Post-Marathon Biochemical Analysis **Context:** A runner just finished a marathon. --- #### (a) Which hormone is being secreted into the blood: insulin or glucagon? From which organ and cell type? **Answer:** - **Hormone:** (Answer pending) - **Organ:** (Answer pending) - **Cell Type:** (Answer pending) --- #### (b) What is the secondary messenger (a small molecule) important for the signaling of the hormone? **Answer:** (Answer pending) --- #### (c) For the enzymes listed below, indicate whether the enzyme activity is upregulated (↑) or downregulated (↓) in the muscle and liver, respectively. **Table of Enzyme Regulation:** | Enzyme | Muscle | Liver | |--------------------------------|--------|-------| | (a) Glycogen synthase | | | | (b) Phosphofructokinase-1 | | | | (c) Fructose-Bisphosphatase-2 | | | | (d) Pyruvate kinase | | | | (e) Pyruvate carboxylase | | | | (f) Acetyl-CoA carboxylase | | | **Note:** The fill-in for regulation status (↑ or ↓) should be provided based on the knowledge of metabolic responses post-exercise, which is not indicated in the provided text. --- ### Explanation of Graphs or Diagrams There are no graphs or diagrams in the provided image. --- #### Educational Context This exercise is designed to evaluate understanding of metabolic and hormonal regulation in response to endurance exercise such as a marathon. It touches on key biochemical principles including hormone signaling and enzyme regulation. Students should be able to: 1. Identify which hormone (insulin or glucagon) would dominate in a post-marathon scenario and understand its origin and the type of cells secreting it. 2. Understand the role and identity of secondary messengers in hormone signaling. 3. Deduce the regulatory response (upregulation or downregulation) of key metabolic enzymes in muscle and liver tissues post-exercise. Students are encouraged to review the metabolic pathways and hormone signaling mechanisms to accurately complete the table and answers.
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