5. Molecular structure and principle of action of ATP synthase.
5. Molecular structure and principle of action of ATP synthase.
6. Inhibitors of electron transport in the respiratory chain of mitochondria.
7. Inhibitors of oxidative phosphorylation in the respiratory chain of mitochondria.
8. Uncouplers of electron transport and oxidative phosphorylation in the respiratory chain of mitochondria.
9. Physiologically active compounds - uncouplers of electron transport and oxidative phosphorylation in the respiratory chain of mitochondria.
10. The role of electron transport uncouplers and oxidative phosphorylation in the regulation of thermogenesis in humans and animals.
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ATP is highly unstable compound which spontaneously dissociates into its products (ADP+Pi ) and releases high energy which is fetched by other nonspontaneous reactions. ATP has two ‘high-energy’ phophoanhydride bonds which are highly unstable and have high stored bond energy, whereas, phosphoester bond is stable and requires high energy to dissociate the bond.
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