Q9: Which of the following processes are decreased by ethanol consumption? Cytosol Mitochondrion A. PATHWAY 1. major pathway of ethanol metabolism NAD* NADH + H* NAD* NADH + H* in the liver CH,-CH,-OH ADH + CH,-C=O CH;-C-OH + H-O-H ALDH ETHANOL ACETALDEHYDE АСЕТАТЕ WATER B. PATHWAY 2 microsomal ethanol CYP2E1 oxidizing system (MEOS) NADPH + H* + O2 NADP* + 2H,O Excess alcohol consumption increases the NADH:NAD* ratio in the cytosol of hepatocytes.
Q9: Which of the following processes are decreased by ethanol consumption? Cytosol Mitochondrion A. PATHWAY 1. major pathway of ethanol metabolism NAD* NADH + H* NAD* NADH + H* in the liver CH,-CH,-OH ADH + CH,-C=O CH;-C-OH + H-O-H ALDH ETHANOL ACETALDEHYDE АСЕТАТЕ WATER B. PATHWAY 2 microsomal ethanol CYP2E1 oxidizing system (MEOS) NADPH + H* + O2 NADP* + 2H,O Excess alcohol consumption increases the NADH:NAD* ratio in the cytosol of hepatocytes.
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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Step 1
In the human body, three steps are involved in alcohol metabolism.
- Ethanol is oxidized to acetaldehyde in the first step by the alcohol dehydrogenase enzyme.
- In the second step, the aldehyde dehydrogenase enzyme is used to convert acetaldehyde to acetate.
- The acetate is converted to acetyl CoA in the third step.
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