5. Ertugliflozin is a medication for the treatment of type 2 diabetes. OH 5.1 5.2 HO HO OH .CI Look at the structure and identify one of the following groups hemiacetal/acetal/hemiketal/ketal. Circle and label it. Based on your identification above, predict the stability of Ertugliflozin under aqueous acidic and basic conditions. Complete the sentence: Ertugliflozin is stable under aqueous acidic/basic unstable under aqueous conditions. acidic/basic conditions and 5.3 Support your predication by providing arrow-pushing mechanism for the hydrolysis reaction under the conditions you chose above. Use HA or B as needed.

Organic Chemistry
8th Edition
ISBN:9781305580350
Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Chapter19: Enolate Anions And Enamines
Section: Chapter Questions
Problem 19.67P
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5. Ertugliflozin is a medication for the treatment of type 2 diabetes.
OH
HO
5.2
HO-
OH
.CI
5.1 Look at the structure and identify one of the following groups
hemiacetal/acetal/hemiketal/ketal. Circle and label it.
Based on your identification above, predict the stability of Ertugliflozin under
aqueous acidic and basic conditions. Complete the sentence:
Ertugliflozin is stable under aqueous
acidic/basic
unstable under aqueous
conditions.
acidic/basic
conditions and
5.3 Support your predication by providing arrow-pushing mechanism for the hydrolysis
reaction under the conditions you chose above. Use HA or B as needed.
Transcribed Image Text:5. Ertugliflozin is a medication for the treatment of type 2 diabetes. OH HO 5.2 HO- OH .CI 5.1 Look at the structure and identify one of the following groups hemiacetal/acetal/hemiketal/ketal. Circle and label it. Based on your identification above, predict the stability of Ertugliflozin under aqueous acidic and basic conditions. Complete the sentence: Ertugliflozin is stable under aqueous acidic/basic unstable under aqueous conditions. acidic/basic conditions and 5.3 Support your predication by providing arrow-pushing mechanism for the hydrolysis reaction under the conditions you chose above. Use HA or B as needed.
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