5. a. About how many molecules of histone H2A wouldbe required in a typical human cell just after thecompletion of S phase, assuming an average nucleosome spacing of 200 bp?b. During what stage of the cell cycle is it most crucial to synthesize new histone proteins?c. The human genome contains 60 histone genes,with 10–15 genes of each type (H1, H2A, H2B,H3, and H4). Why do you think the genome contains multiple copies of each histone gene?

Q: 2. a) In the diagram of DNA below (Figure 4), a DNA strandis unwinding and new strands of DNA are…

A: The unwinding of DNA helix takes place with the help of enzyme DNA helicase. Addition of nucleotides…

Q: How would you design an experiment to test the hypothesis: Alpha tubulin is expressed at higher…

A: Alpha tubulin is a major component of cytoskeleton in eukaryotes. During cell division, this protein…

Q: a. What is your epigenome (i.e. epigenetics)? b. Does lifestyle affect your epigenome? Explain c.…

A: Hi! Thank you for the question. As the question is based on watching a video and external references…

Q: In the eukaryotic nucleus during interphase, a strand of chromatin consisting of eight conserved…

A: Interphase is the part of the cell cycle that is not followed by significant changes under the…

Q: 4. a. Give at least three examples of types of mutationsthat would disrupt the process of mitotic…

A: Since you have asked multiple questions, we will solve the first question for you. If you want any…

Q: 6.) How does RNAi maintain the heterochromatin at the centromeres of chromosomes?

A: Heterochromatin is a form of DNA (deoxyribonucleic acid) that is dense or closely packed. It varies…

Q: 1. What does heterochromatin mean? a. The genes are expressed and it is involved with gene…

A: Gene expression is a process by which the genes are turned on to form RNA and proteins.…

Q: 12.

A: Gene expression refers to the process by which the genetic information encoded within a gene is used…

Q: To further understand lysosomal function, you have created mouse cell lines, each with a different…

A: * Mouse cell lines have created and each with a different lysosomal defect. *The first line A1…

Q: 6. This is where the RNA polymerase is bound and a short region of DNA is accessible to begin the…

A: In bacteria,The RNA poltmerase enzyme binds and unwinds promoter DNA and open promoter complex form…

Q: Think about the important functions of telomeres. Now, imagine a scenario in which a mutant…

A: Introduction  Telomeres are repeating sequences that protect the natural ends of linear eukaryotic…

Q: 1.Generally, demethylation on the promoter region of a gene blocks transcription. True\False?…

A: Disclaimer: - According to the Bartleby guidelines, only the first three true/false questions can be…

Q: Which of the following molecules is designed to deliver drugs to the body cells? O a. Proteasome O…

A: "Since you have asked multiple questions, according to Bartleby's guidelines we are eligible to…

Q: Explain how chromatin can affect gene expression in eukaryotes. and transcription is When DNA is…

A: Chromatin is a decondensed state of chromosomes. It is present in interphase and telophase stage in…

Q: 3). Consider the four mutations (i-iv) described below: i. One of the mutations causing cystic…

A: A mutation is a permanent change in the DNA sequence of an organism's genome. Mutations can occur…

Q: During synapsis a. sister chromatids pair all along their length b. sister chromatids pair at the…

A: During meiosis, the pairing of two chromosomes is known as synapsis. It requires homologous pairs to…

Q: 1.In which phase of the cell cycle are DNA mutations most likely to occur? A.S Phase B.G1 Phase…

A: Mutation - Mutation is defined as the sudden inheritable changes which occurs either in the…

Q: .what Human diseases that result from variations in multiple genes?

A: NOTE- As per our honor code, we are authorized to answer only one question at a moment. As you have…

Q: Draw and describe the “beads on a string” structure of the chromatin. 4. What are the proteins found…

A: The haploid human genome contains approximately three billion base pairs of DNA. Each base pair is…

Q: Discuss the structure and functions of the prokaryotic structures covered in class: cell wall,…

A: NOTE- As per our Bartleby Q/A guidelines we are only allowed to answer top three questions if you…

Q: 1. Regarding nucleosome structure, which of the following statements is correct? A. Nucleosomesare…

A: Chromatin is a complex made of DNA and protein in equal proportion along with small amounts of RNA.…

Q: When a particular mutagen is identified by the Ames test and injected into mice (group A), it causes…

A: Ames test is the widely practiced method that is used to determine whether a chemical(mutagen) can…

Q: DNA polymerase III can correct replication errors through its ________ activity. a. 3’ to 5’…

A: Introduction: Although DNA replication is a highly precise process, errors such as a DNA polymerase…

Q: During the last stages of pregnancy, the mammary glands (glands that produce milk) develop, where…

A: Protein synthesis is guided by the central dogma that is universal in living things. Proteins are…

Q: 3. One hallmark of cancer cells is their ability to divide indefinitely, in contrast with most…

A: Telomeres are conserved sequences which can be considered as protective structures present at the…

Q: 8. For each of the following DNA template strands a. 3' TACGGC 5' b. 3' CCATTA 5' Determine: a. the…

A: The heterogenous nuclear ribonucleoprotein (hnRNP) is the  initial step of synthesizing mRNA during…

Q: 3. You are investigating an abnormal eukaryotic cell line that makes mRNAs much longer than the…

A: mRNAs are single-stranded RNA molecules that are complementary to one of the DNA strands of a gene.…

Q: 2. The yeast gene encoding a protein found in themitotic spindle was cloned by a laboratory…

A: A protein is encoded by the yeast gene that is found in the mitotic spindle. This gene is cloned by…

Q: 2. Chronic myeloid leukemia (CML) is a blood cancer with adult onset. In most CML patients, The…

A: Chronic myeloid leukemia (CML) is a blood cancer that often involves the Philadelphia Chromosome…

Q: Daisy inherits a mutation from her mother that results in the phenotype of red hair. Evegny acquires…

A: Introduction A mutation occurs when the sequence of DNA is altered. Mutations can occur as a result…

Q: 7. The beoads on a string in the picture represent what in terms OE DRA 20lding? "Beads on a string"…

A: Template strand is also known as sense strand. This is actively involved in transcription. The…

Q: 6. You are studying an anaerobic, unicellular eukaryote that lacks mitochondria. Strangely, the…

A: Finding mitochondrial genes in the nucleus of an anaerobic, unicellular eukaryote that lacks…

Q: 5. In the human species, it was found that 19% of Cytosine was present. Calculate the % of Adenine.…

A: Gene is the primary fundamental unit of heredity. This is found in the nucleus of the eukaryotic…

Q: 25. Which of the following describes the role of acetylation during the chromatin remodeling that…

A: Chromatin remodeling refers to the dynamic changes in the structure of chromatin, the complex of DNA…

Q: A disease is caused by having no functional protein produced from the KIP gene. An individual has…

A: The gene expression follow the rules of central dogma that involves production of the final product…

Q: . How do I explain a brief outline of the mechanisms in which DNA is used to generate protein by…

A: “Since you have asked multiple questions, we will solve the first question for you. If you want any…

Q: 3. A drug serves to inhibit acetylation on chromatin structure. This would lead to the DNA being in…

A: Answer :  Hypoacetylation (normally absent , hypoacetylation) (biochemistry) inadequate acetylation…

Q: 2. Which ONE of these statements on chromatin modification is UNTRUE? O DNA is methylated on the…

A: Introduction The dynamic modification of chromatin architecture to allow access of condensed genomic…

Q: 9. Which one of the following histones is a component of the core particle? A. H1 B. H2A C. H2B D.…

A: In 1868, Swiss physician Friedrich Miescher extracted nucleic acids from the nucleus of white blood…

Q: 3. Haplopappus is an annual flowering plant that grows in deserts. It is of interest because its 2n…

A: Introduction The cell cycle is the sequence of events that occur in a cell leading to its division…

Q: List in the correct order the series of cytoskeletal events that occurs in a newly fertilized egg of…

A: Caenorhabditis elegans is now the model organism of choice for researchers. A combination of its…

Q: 19. In healthy cells, Gene Z is required for cell cycle progression. A patient goes to an oncologist…

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Genome annotation

The technique of linking biological information to genome sequences is termed genome annotation. Gene annotation is the method of identifying gene locations and coding sections. It helps us understand what these genes are doing in the body through establishing structural characteristics and linking them to the actions of various proteins.