5 Worksheet: Chirality - Handedness of Molecules 1 Label the chirality center/stereocenter in the given molecules using an asterisk. The compounds contain zero or one chirality center. H a. CH3CHCH2CH3 b. (CH3)3CH C. CH2=CHCHCH3 d. C-CH3 OH Br 2 Label the chirality center in each drug. 3 4 6 a. Br H b. CH2CH2N(CH3)2 brompheniramine (antihistamine) CH2CH2NHCH3 fluoxetine Trade name: Prozac (antidepressant) -CF3 Mark each stereocenter in these molecules with an asterisk. Note that not all contain stereocenters. OH OH HO OH HO b. a. OH OH Locate the chirality center: (a) fluoxetine, an antidepressant; (b) sertraline, the generic name for the antidepressant Zoloft. CH2CH2NHCH3 fluoxetine Trade name: Prozac (antidepressant) -CF3 CH3NH- Label the chirality center in each compound and draw both enantiomers. a. CH3CHCH2CH3 b. CH3CH2CHCH2OH OH sertraline Propranolol (trade name: Inderal) is used in the treatment of high blood pressure and heart disease. (a) Locate the chirality center in propranolol. (b) Draw both enantiomers of propranolol. OCH2CHCH2NHCH(CH3)2 он propranolol

Organic Chemistry: A Guided Inquiry
2nd Edition
ISBN:9780618974122
Author:Andrei Straumanis
Publisher:Andrei Straumanis
Chapter12: Chirality
Section: Chapter Questions
Problem 19E
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5
Worksheet: Chirality - Handedness of Molecules
1
Label the chirality center/stereocenter in the given molecules using an asterisk. The compounds contain zero or one
chirality center.
H
a. CH3CHCH2CH3
b. (CH3)3CH
C. CH2=CHCHCH3
d.
C-CH3
OH
Br
2
Label the chirality center in each drug.
3
4
6
a. Br
H
b.
CH2CH2N(CH3)2
brompheniramine
(antihistamine)
CH2CH2NHCH3
fluoxetine
Trade name: Prozac
(antidepressant)
-CF3
Mark each stereocenter in these molecules with an asterisk. Note that not all contain stereocenters.
OH
OH
HO
OH
HO
b.
a.
OH
OH
Locate the chirality center: (a) fluoxetine, an antidepressant; (b) sertraline, the generic name for the antidepressant Zoloft.
CH2CH2NHCH3
fluoxetine
Trade name: Prozac
(antidepressant)
-CF3
CH3NH-
Label the chirality center in each compound and draw both enantiomers.
a. CH3CHCH2CH3
b. CH3CH2CHCH2OH
OH
sertraline
Propranolol (trade name: Inderal) is used in the treatment of high blood pressure and heart disease.
(a) Locate the chirality center in propranolol. (b) Draw both enantiomers of propranolol.
OCH2CHCH2NHCH(CH3)2
он
propranolol
Transcribed Image Text:5 Worksheet: Chirality - Handedness of Molecules 1 Label the chirality center/stereocenter in the given molecules using an asterisk. The compounds contain zero or one chirality center. H a. CH3CHCH2CH3 b. (CH3)3CH C. CH2=CHCHCH3 d. C-CH3 OH Br 2 Label the chirality center in each drug. 3 4 6 a. Br H b. CH2CH2N(CH3)2 brompheniramine (antihistamine) CH2CH2NHCH3 fluoxetine Trade name: Prozac (antidepressant) -CF3 Mark each stereocenter in these molecules with an asterisk. Note that not all contain stereocenters. OH OH HO OH HO b. a. OH OH Locate the chirality center: (a) fluoxetine, an antidepressant; (b) sertraline, the generic name for the antidepressant Zoloft. CH2CH2NHCH3 fluoxetine Trade name: Prozac (antidepressant) -CF3 CH3NH- Label the chirality center in each compound and draw both enantiomers. a. CH3CHCH2CH3 b. CH3CH2CHCH2OH OH sertraline Propranolol (trade name: Inderal) is used in the treatment of high blood pressure and heart disease. (a) Locate the chirality center in propranolol. (b) Draw both enantiomers of propranolol. OCH2CHCH2NHCH(CH3)2 он propranolol
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