4. Terpenes are substances derived from active isoprene or isopropyl pyrophosphate, they are the main constituent of the essential oils of some plants and flowers. Terpenes can be formed through biosynthetic reactions, one of the fundamental compounds one of the precursors in these biosynthetic pathways is isopentenyl diphosphate IPP. a) Propose a precursor for said compound through an elimination reaction and draw the reaction mechanism. B) What other product could be formed in this proposed transformation? OP2O6H3 IPP

Organic Chemistry
8th Edition
ISBN:9781305580350
Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Chapter21: Benzene And The Concept Of Aromaticity
Section: Chapter Questions
Problem 21.56P
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Terpenes are substances derived from active isoprene or isopropyl pyrophosphate, they are the main
constituent of the essential oils of some plants and flowers. Terpenes can be formed through
biosynthetic reactions, one of the fundamental compounds one of the precursors in these
biosynthetic pathways is isopentenyl diphosphate IPP. a) Propose a precursor for said compound
through an elimination reaction and draw the reaction mechanism. B) What other product could be
formed in this proposed transformation?
4.
OP206H3
+
IPP
5. Among many of the drugs studied for the treatment of cancer is the carboxamide derivative Poly
(ADP-ribose) polymerase inhibitor. This derivative is synthesized through an elimination reaction
using the reagent methanesulfonyl chloride. 1. Write the major elimination product. 2. Write the
possible secondary product.3. Indicate the reasons why this product is considered to be the major
product (the one described in the resolution by you).
Et
DBU
OBи +
CI-
S-CH3
2 h, Reflux
НО
CH2CI2
(94 % mayoritario)
Transcribed Image Text:Terpenes are substances derived from active isoprene or isopropyl pyrophosphate, they are the main constituent of the essential oils of some plants and flowers. Terpenes can be formed through biosynthetic reactions, one of the fundamental compounds one of the precursors in these biosynthetic pathways is isopentenyl diphosphate IPP. a) Propose a precursor for said compound through an elimination reaction and draw the reaction mechanism. B) What other product could be formed in this proposed transformation? 4. OP206H3 + IPP 5. Among many of the drugs studied for the treatment of cancer is the carboxamide derivative Poly (ADP-ribose) polymerase inhibitor. This derivative is synthesized through an elimination reaction using the reagent methanesulfonyl chloride. 1. Write the major elimination product. 2. Write the possible secondary product.3. Indicate the reasons why this product is considered to be the major product (the one described in the resolution by you). Et DBU OBи + CI- S-CH3 2 h, Reflux НО CH2CI2 (94 % mayoritario)
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