Just need answer to question 4 133.8.3.8You are a genetic counselor and a couple has come to you for advice. They have a family history ofcancer and are concerned that their unborn third child will also get cancer. They provide you withthe following pedigrees for two different traits relating to defects in the enzymes separase andtopoisomerase:A.SeparasedefectB.Topoisomerasedefect421.4.6.6.9.6.5.5.111213111214151415These two pedigrees represent the same family. Genetic testing shows that individual 4 has onlynonmutant alleles of both genes and individual 12 has only mutant alleles of both genes. Individuals6, 8, 9, 12, and 14 have cancer. The couple just recently learned that their daughter (individual 14)has cancer and has both mutations. In this lab activity, you will use Punnett squares to determinethe probability that the couple's third unborn child will also inherit both mutations and be at riskfor developing cancer..Using Punnett squares, determine the phenotypes of offspring that the following parents couldproduce. For some situations, there could be more than one genotype for at least one of the parents.In these cases, be sure to include Punnett squares for all possibilities, and give the probablilty thattheir third unborn child may be at risk for developing cancer.1. An autosomal recessive trait with an unaffected mother and an affected father.2. An autosomal dominant trait with an affected mother and an unaffected father.3. An X-linked recessive trait with an unaffected mother and an affected father.4. An X-linked dominant trait with an unaffected mother and an affected father.

X linked dominant This type of Inheritance refers to the mutations in the genes that are present on…

Answered: 4. An X-linked dominant trait with an…

Science

Biology

4. An X-linked dominant trait with an unaffected mother and an affected father.

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter15: Genomes And Genomics

Section: Chapter Questions

Problem 14QP

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Question

Just need answer to question 4

13
3.
8.
3.
8
You are a genetic counselor and a couple has come to you for advice. They have a family history of
cancer and are concerned that their unborn third child will also get cancer. They provide you with
the following pedigrees for two different traits relating to defects in the enzymes separase and
topoisomerase:
A.
Separase
defect
B.
Topoisomerase
defect
4
2
1.
4.
6.
6.
9.
6.
5.
5.
11
12
13
11
12
14
15
14
15
These two pedigrees represent the same family. Genetic testing shows that individual 4 has only
nonmutant alleles of both genes and individual 12 has only mutant alleles of both genes. Individuals
6, 8, 9, 12, and 14 have cancer. The couple just recently learned that their daughter (individual 14)
has cancer and has both mutations. In this lab activity, you will use Punnett squares to determine
the probability that the couple's third unborn child will also inherit both mutations and be at risk
for developing cancer.
.Using Punnett squares, determine the phenotypes of offspring that the following parents could
produce. For some situations, there could be more than one genotype for at least one of the parents.
In these cases, be sure to include Punnett squares for all possibilities, and give the probablilty that
their third unborn child may be at risk for developing cancer.
1. An autosomal recessive trait with an unaffected mother and an affected father.
2. An autosomal dominant trait with an affected mother and an unaffected father.
3. An X-linked recessive trait with an unaffected mother and an affected father.
4. An X-linked dominant trait with an unaffected mother and an affected father.

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