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38. a Stool frequency after 2, 4 and 6 weeks of treatment -0.4 Stool frequency (Estimated effect ± 95% CI) -0.2 0.0 p=0.090 p=0.083 0.2 0.4 b Stool consistency after 2, 4 and 6 weeks of treatment Stool consistency (Estimated effect ± 95% CI) 2 p=0.023 H -1.5 O p=0.046 -1.0 -0.5 0.5 1.0 Favors EpiCor Favors placebo 0.0 1.5 o Total cohort o Severe subgroup Moderate subgroup Favors EpiCor Favors placebo Fig. 4 Mean differences between EpiCor and placebo on stool frequency (a) and consistency (b) on the three cohorts. Legend: A linear mixed model analysis that takes into account the differences between groups at baseline was used (p-values <0.05 are depicted in bold text, p-values <0.1 are depicted in regular text) The figure above is from a study by Pinheiro et al. (2017) on a nutritional ingredient called 'EpiCor'; that looks at its effects on GI discomfort and constipation. The figure depicts the effects of EpiCor on stool frequency and stool consistency in the overall cohort (moderate+severe), the 'moderate' symptoms subgroup and the 'severe' symptoms subgroup. Based on the figure, answer the following questions: A. Did EpiCor have a significant effect on stool frequency? If so, at what time points and in which group was the effect noted? B. Did EpiCor have a significant effect on stool consistency? Is so, at what time points and in which group was the effect noted? C. What statistical analysis would you use for analyzing this data?

38. a Stool frequency after 2, 4 and 6 weeks of treatment -0.4 Stool frequency (Estimated effect ± 95% CI) -0.2 0.0 p=0.090 p=0.083 0.2 0.4 b Stool consistency after 2, 4 and 6 weeks of treatment Stool consistency (Estimated effect ± 95% CI) 2 p=0.023 H -1.5 O p=0.046 -1.0 -0.5 0.5 1.0 Favors EpiCor Favors placebo 0.0 1.5 o Total cohort o Severe subgroup Moderate subgroup Favors EpiCor Favors placebo Fig. 4 Mean differences between EpiCor and placebo on stool frequency (a) and consistency (b) on the three cohorts. Legend: A linear mixed model analysis that takes into account the differences between groups at baseline was used (p-values <0.05 are depicted in bold text, p-values <0.1 are depicted in regular text) The figure above is from a study by Pinheiro et al. (2017) on a nutritional ingredient called 'EpiCor'; that looks at its effects on GI discomfort and constipation. The figure depicts the effects of EpiCor on stool frequency and stool consistency in the overall cohort (moderate+severe), the 'moderate' symptoms subgroup and the 'severe' symptoms subgroup. Based on the figure, answer the following questions: A. Did EpiCor have a significant effect on stool frequency? If so, at what time points and in which group was the effect noted? B. Did EpiCor have a significant effect on stool consistency? Is so, at what time points and in which group was the effect noted? C. What statistical analysis would you use for analyzing this data?

MATLAB: An Introduction with Applications
MATLAB: An Introduction with Applications
6th Edition
ISBN:9781119256830
Author:Amos Gilat
Publisher:Amos Gilat
Chapter1: Starting With Matlab
Section: Chapter Questions
Problem 1P
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38. a Stool frequency after 2, 4 and 6 weeks of treatment Stool frequency (Estimated effect ± 95%CI) -0.4 -0.2 p=0.090 0.0 p=0.083 0.2 b 0.4 Stool consistency after 2, 4 and 6 weeks of treatment Stool consistency (Estimated effect ± 95% Cl) -1.5 -1.0 -0.5 0.0 0.5 1.0 Favors EpiCor Favors placebo Favors EpiCor Favors placebo Fig. 4 Mean differences between EpiCor and placebo on stool frequency (a) and consistency (b) on the three cohorts. Legend: A linear mixed model analysis that takes into account the differences between groups at baseline was used (p-values <0.05 are depicted in bold text, p-values <0.1 are depicted in regular text) 2 p=0.023 H C p=0.046 o Total cohort o Severe subgroup Moderate subgroup 1.5 The figure above is from a study by Pinheiro et al. (2017) on a nutritional ingredient called 'EpiCor'; that looks at its effects on GI discomfort and constipation. The figure depicts the effects of EpiCor on stool frequency and stool consistency in the overall cohort (moderate+severe), the 'moderate' symptoms subgroup and the 'severe' symptoms subgroup. Based on the figure, answer the following questions: A. Did EpiCor have a significant effect on stool frequency? If so, at what time points and in which group was the effect noted? (1 B. Did EpiCor have a significant effect on stool consistency? Is so, at what time points and in which group was the effect noted? C. What statistical analysis would you use for analyzing this data?
Transcribed Image Text:38. a Stool frequency after 2, 4 and 6 weeks of treatment Stool frequency (Estimated effect ± 95%CI) -0.4 -0.2 p=0.090 0.0 p=0.083 0.2 b 0.4 Stool consistency after 2, 4 and 6 weeks of treatment Stool consistency (Estimated effect ± 95% Cl) -1.5 -1.0 -0.5 0.0 0.5 1.0 Favors EpiCor Favors placebo Favors EpiCor Favors placebo Fig. 4 Mean differences between EpiCor and placebo on stool frequency (a) and consistency (b) on the three cohorts. Legend: A linear mixed model analysis that takes into account the differences between groups at baseline was used (p-values <0.05 are depicted in bold text, p-values <0.1 are depicted in regular text) 2 p=0.023 H C p=0.046 o Total cohort o Severe subgroup Moderate subgroup 1.5 The figure above is from a study by Pinheiro et al. (2017) on a nutritional ingredient called 'EpiCor'; that looks at its effects on GI discomfort and constipation. The figure depicts the effects of EpiCor on stool frequency and stool consistency in the overall cohort (moderate+severe), the 'moderate' symptoms subgroup and the 'severe' symptoms subgroup. Based on the figure, answer the following questions: A. Did EpiCor have a significant effect on stool frequency? If so, at what time points and in which group was the effect noted? (1 B. Did EpiCor have a significant effect on stool consistency? Is so, at what time points and in which group was the effect noted? C. What statistical analysis would you use for analyzing this data?
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