36. A 3-month-old boy is brought to the emergency department because of a 2-day history of lethargy. Physical examination shows no other abnormalities. The results of laboratory studies are shown: Serum Na+ 165 mEq/L (N=139-146) 130 mEq/L (N=95-105) CI- Osmolality Urine 334 mOsmol/kg H₂O (N=282-295) 1.001 Specific gravity Osmolality 117 mOsmol/kg H₂O (N>200) He is admitted to the hospital. His urine output is increased. His serum ADH (vasopressin) concentration is 24 pg/mL (N=1-5); aldosterone and renin concentrations are within the reference ranges. The urine osmolality remains unchanged after administration of 1-deamino-8-arginine vasopressin. An MRI of the brain and pituitary gland shows no abnormalities. Ultrasonography shows normal kidneys. The most likely underlying cause of the findings in this patient is a defect in which of the following? A) Angiotensin-converting enzyme B) Aquaporin OC) 11a-Hydroxylase D) Renin E) Vasopressin receptors
36. A 3-month-old boy is brought to the emergency department because of a 2-day history of lethargy. Physical examination shows no other abnormalities. The results of laboratory studies are shown: Serum Na+ 165 mEq/L (N=139-146) 130 mEq/L (N=95-105) CI- Osmolality Urine 334 mOsmol/kg H₂O (N=282-295) 1.001 Specific gravity Osmolality 117 mOsmol/kg H₂O (N>200) He is admitted to the hospital. His urine output is increased. His serum ADH (vasopressin) concentration is 24 pg/mL (N=1-5); aldosterone and renin concentrations are within the reference ranges. The urine osmolality remains unchanged after administration of 1-deamino-8-arginine vasopressin. An MRI of the brain and pituitary gland shows no abnormalities. Ultrasonography shows normal kidneys. The most likely underlying cause of the findings in this patient is a defect in which of the following? A) Angiotensin-converting enzyme B) Aquaporin OC) 11a-Hydroxylase D) Renin E) Vasopressin receptors
Chapter9: Parenteral Medication Labels And Dosage Calculation
Section: Chapter Questions
Problem 4.8P
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Transcribed Image Text:36. A 3-month-old boy is brought to the emergency department because of a 2-day history of lethargy. Physical examination shows no other abnormalities. The results of
laboratory studies are shown:
Serum
Na+
165 mEq/L (N=139-146)
CI-
130 mEq/L (N=95-105)
334 mOsmol/kg H₂O (N=282-295)
Osmolality
Urine
1.001
Specific gravity
Osmolality
117 mOsmol/kg H₂O (N>200)
He is admitted to the hospital. His urine output is increased. His serum ADH (vasopressin) concentration is 24 pg/mL (N=1-5); aldosterone and renin concentrations
are within the reference ranges. The urine osmolality remains unchanged after administration of 1-deamino-8-arginine vasopressin. An MRI of the brain and pituitary
gland shows no abnormalities. Ultrasonography shows normal kidneys. The most likely underlying cause of the findings in this patient is a defect in which of the
following?
A) Angiotensin-converting enzyme
B) Aquaporin
C) 11a-Hydroxylase
D) Renin
E) Vasopressin receptors
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