3. Plants of the Euphorbia genus exude a "milky irritant latex" and have a wide range of medically relevant activities (antiviral, anti-proliferative, anti-inflammatory, anti- drug resistance). The natural product (+)-pepluanol A, a secondary metabolite of Euphorbia, has recently been synthesized. (Yuan, P.; Gaich, T.; Org. Lett., 2022, in press.) a) How many chiral centers does (+)-pepluanol A have? b) In which direction does pure (+)-pepluanol A rotate the plane of polarized light? Me Me Me,,, "H X H Me Me (+)-pepluanol A I Me OH

Organic Chemistry
9th Edition
ISBN:9781305080485
Author:John E. McMurry
Publisher:John E. McMurry
Chapter28: Biomolecules: Nucleic Acids
Section28.SE: Something Extra
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3. Plants of the Euphorbia genus exude a "milky irritant latex" and have a wide range
of medically relevant activities (antiviral, anti-proliferative, anti-inflammatory, anti-
drug resistance). The natural product (+)-pepluanol A, a secondary metabolite of
Euphorbia, has recently been synthesized. (Yuan, P.; Gaich, T.; Org. Lett., 2022, in
press.)
a) How many chiral centers does (+)-pepluanol A have?
b) In which direction does pure (+)-pepluanol A rotate the plane of polarized light?
Me,,
Me Me
Me
$
"H
H
OH
Me
Me
(+)-pepluanol A
Transcribed Image Text:3. Plants of the Euphorbia genus exude a "milky irritant latex" and have a wide range of medically relevant activities (antiviral, anti-proliferative, anti-inflammatory, anti- drug resistance). The natural product (+)-pepluanol A, a secondary metabolite of Euphorbia, has recently been synthesized. (Yuan, P.; Gaich, T.; Org. Lett., 2022, in press.) a) How many chiral centers does (+)-pepluanol A have? b) In which direction does pure (+)-pepluanol A rotate the plane of polarized light? Me,, Me Me Me $ "H H OH Me Me (+)-pepluanol A
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