teases are enzymes that can break covalent bonds in proteins. Proteases play major roles in the regulation of biological processes, ompounds that inhibit their function, called protease inhibitors, have potential as therapeutic agents. While preparing several ential protease inhibitors, compound 1 was converted into compound 3 via alkyne 2, as shown. (J. Org. Chem. 1989, 54, 3963- 2) Draw the structure of alkyne 2, and propose reagents for converting 1 into 3. -p1 Br 2 alle--ell (~-10) Ph = Br Br Br Ph O Edit Drawing 1 OH OH O lodify the given structure of 1 to draw alkyne 2. An eraser is available, and you can use the single bond tool to add/remove pi onds. Ph 3 OH
Types of Chemical Bonds
The attractive force which has the ability of holding various constituent elements like atoms, ions, molecules, etc. together in different chemical species is termed as a chemical bond. Chemical compounds are dependent on the strength of chemical bonds between its constituents. Stronger the chemical bond, more will be the stability in the chemical compounds. Hence, it can be said that bonding defines the stability of chemical compounds.
Polarizability In Organic Chemistry
Polarizability refers to the ability of an atom/molecule to distort the electron cloud of neighboring species towards itself and the process of distortion of electron cloud is known as polarization.
Coordinate Covalent Bonds
A coordinate covalent bond is also known as a dative bond, which is a type of covalent bond. It is formed between two atoms, where the two electrons required to form the bond come from the same atom resulting in a semi-polar bond. The study of coordinate covalent bond or dative bond is important to know about the special type of bonding that leads to different properties. Since covalent compounds are non-polar whereas coordinate bonds results always in polar compounds due to charge separation.
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