3. KRAS the most common gene mutation in non-small cell lung cancer (NSCLC) that is oncogenic (driving development of tumors). Using data from the registry of the American Association for Cancer Research Project Genomics Evidence Neoplasia Information Exchange (GENIE), researchers demonstrated potential differences in the rate of KRASG¹2C mutations by race. https://www.nejm.org/doi/full/10.1056/NEJMc2030638 Among patients with NSCLC in the GENIE cohort, White and Black patient groups had higher rates of KRASG¹2C mutations than Asians (White patients, 1153 of 8892 [13%]; Black patients, 94 of 862 [11%]; and Asian patients, 25 of 690 [4%]). a. What is the KRASG¹2C mutation rate across all 3 race groups? (Note: total of 10444 patients with NSCLC in the GENIE data) b. Suppose a given person with NSCLC in the GENIE data has the KRASG¹2C mutation, what are the chances they are Asian?

3. KRAS the most common gene mutation in non-small cell lung cancer (NSCLC) that is oncogenic (driving development of tumors). Using data from the registry of the American Association for Cancer Research Project Genomics Evidence Neoplasia Information Exchange (GENIE), researchers demonstrated potential differences in the rate of KRASG¹2C mutations by race. https://www.nejm.org/doi/full/10.1056/NEJMc2030638 Among patients with NSCLC in the GENIE cohort, White and Black patient groups had higher rates of KRASG¹2C mutations than Asians (White patients, 1153 of 8892 [13%]; Black patients, 94 of 862 [11%]; and Asian patients, 25 of 690 [4%]). a. What is the KRASG¹2C mutation rate across all 3 race groups? (Note: total of 10444 patients with NSCLC in the GENIE data) b. Suppose a given person with NSCLC in the GENIE data has the KRASG¹2C mutation, what are the chances they are Asian?

A First Course in Probability (10th Edition)

10th Edition

ISBN:9780134753119

Author:Sheldon Ross

Publisher:Sheldon Ross

Chapter1: Combinatorial Analysis

Section: Chapter Questions

Problem 1.1P: a. How many different 7-place license plates are possible if the first 2 places are for letters and...

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