3. Glycine is a diprotic acid that can undergo two dissociation reactions, one for the a-amino group and the other for the carboxyl group. Therefore, it has two pKa values. The carboxyl group has a pKa1 of 2.34 and the a-amino group has a pKa2 of 9.60. Glycine can exist in fully deprotonated, fully protonated or zwitterionic form. 天 H H H H H H H ΝΘ он он H C-H H- -H H-C-H H O-H ion at low pH zwitterion neutral pH ion at high pH Determine the concentrations of glycine's different protonated forms at a. pH 2.0 b. pH 5.0 c. pH 12.0

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Chapter22: Organic And Biological Molecules
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3. Glycine is a diprotic acid that can undergo two dissociation reactions, one for the a-amino group and
the other for the carboxyl group. Therefore, it has two pKa values. The carboxyl group has a pKa1 of
2.34 and the a-amino group has a pKa2 of 9.60. Glycine can exist in fully deprotonated, fully protonated
or zwitterionic form.
天
H
H
H
H
H
H
H
ΝΘ
он
он
H
C-H
H-
-H
H-C-H
H
O-H
ion at low pH
zwitterion
neutral pH
ion at high pH
Determine the concentrations of glycine's different protonated forms at
a. pH 2.0
b. pH 5.0
c. pH 12.0
Transcribed Image Text:3. Glycine is a diprotic acid that can undergo two dissociation reactions, one for the a-amino group and the other for the carboxyl group. Therefore, it has two pKa values. The carboxyl group has a pKa1 of 2.34 and the a-amino group has a pKa2 of 9.60. Glycine can exist in fully deprotonated, fully protonated or zwitterionic form. 天 H H H H H H H ΝΘ он он H C-H H- -H H-C-H H O-H ion at low pH zwitterion neutral pH ion at high pH Determine the concentrations of glycine's different protonated forms at a. pH 2.0 b. pH 5.0 c. pH 12.0
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