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Analyze the synthetic route and determine whether the reagents selected are anticipated to work well, poorly, or not at all and the reason why. 1 KCN, Ethanol CH3CH2CH2CH2Cl CH3CH2CH2CH2NH₂ 2 LiAlH4, ether How will the reaction proceed? Not at all. This sequence adds one extra carbon to the chain. Well. KCN is a good nucleophile and LiAlH reduces nitriles readily to amines. Poorly, Cl is not a good leaving group and should be replaced with a Br.

Analyze the synthetic route and determine whether the reagents selected are anticipated to work well, poorly, or not at all and the reason why. 1 KCN, Ethanol CH3CH2CH2CH2Cl CH3CH2CH2CH2NH₂ 2 LiAlH4, ether How will the reaction proceed? Not at all. This sequence adds one extra carbon to the chain. Well. KCN is a good nucleophile and LiAlH reduces nitriles readily to amines. Poorly, Cl is not a good leaving group and should be replaced with a Br.

Organic Chemistry: A Guided Inquiry
Organic Chemistry: A Guided Inquiry
2nd Edition
ISBN:9780618974122
Author:Andrei Straumanis
Publisher:Andrei Straumanis
Chapter14: Elimination
Section: Chapter Questions
Problem 35CTQ
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Analyze the synthetic route and determine whether the reagents selected are anticipated to work well, poorly, or not at all and the reason why. 1 KCN, Ethanol CH3CH2CH2CH2Cl CH3CH2CH2CH2NH₂ 2 LiAlH4, ether How will the reaction proceed? Not at all. This sequence adds one extra carbon to the chain. Well. KCN is a good nucleophile and LiAlH reduces nitriles readily to amines. Poorly, Cl is not a good leaving group and should be replaced with a Br.
Transcribed Image Text:Analyze the synthetic route and determine whether the reagents selected are anticipated to work well, poorly, or not at all and the reason why. 1 KCN, Ethanol CH3CH2CH2CH2Cl CH3CH2CH2CH2NH₂ 2 LiAlH4, ether How will the reaction proceed? Not at all. This sequence adds one extra carbon to the chain. Well. KCN is a good nucleophile and LiAlH reduces nitriles readily to amines. Poorly, Cl is not a good leaving group and should be replaced with a Br.
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