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3. Consider the molecule dopamine (shown). Given that its pKa(NH3*) = 10.9. НО. a. What pH range would dopamine be a good buffer at? b. Draw the structures of the predominant species in solution at (i) pH 7, (ii) pH 10, and (iii) pH 12. c. At what pH range do you expect dopamine to be most water soluble? d. At what pH do you expect dopamine to be most hexane soluble? HO NH3 pka = 10.9

3. Consider the molecule dopamine (shown). Given that its pKa(NH3*) = 10.9. НО. a. What pH range would dopamine be a good buffer at? b. Draw the structures of the predominant species in solution at (i) pH 7, (ii) pH 10, and (iii) pH 12. c. At what pH range do you expect dopamine to be most water soluble? d. At what pH do you expect dopamine to be most hexane soluble? HO NH3 pka = 10.9

Biochemistry
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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3. Consider the molecule dopamine (shown). Given that its pKa(NH3¹) = 10.9. a. What pH range would dopamine be a good buffer at? b. Draw the structures of the predominant species in solution at (i) pH 7, (ii) pH 10, and (iii) pH 12. c. At what pH range do you expect dopamine to be most water soluble? d. At what pH do you expect dopamine to be most hexane soluble? НО. HO + NH3 pka = 10.9
Transcribed Image Text:3. Consider the molecule dopamine (shown). Given that its pKa(NH3¹) = 10.9. a. What pH range would dopamine be a good buffer at? b. Draw the structures of the predominant species in solution at (i) pH 7, (ii) pH 10, and (iii) pH 12. c. At what pH range do you expect dopamine to be most water soluble? d. At what pH do you expect dopamine to be most hexane soluble? НО. HO + NH3 pka = 10.9
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