3. After an IV bolus dose of 500 mg of a drug, the following data were collected: (first order elimination) Time (hrs) Cp (mcg/ml) 1 64 2 48 Determine the following: a) Co b) Rate constant Half-life 3 34 4 25 6 14 8 7.8 10 4.2
3. After an IV bolus dose of 500 mg of a drug, the following data were collected: (first order elimination) Time (hrs) Cp (mcg/ml) 1 64 2 48 Determine the following: a) Co b) Rate constant Half-life 3 34 4 25 6 14 8 7.8 10 4.2
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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
Transcribed Image Text:3. After an IV bolus dose of 500 mg of a drug, the following data were collected:
(first order elimination)
Time (hrs)
Cp (mcg/ml)
1
64
2 3 4
48
34
Determine the following:
a) Co
b) Rate constant
c) Half-life
d) Total area under the curve
87
6
10
25 14 7.8 4.2
Please solve using these equations:
dCp/dt=-k(Cp)
t1/2= 0.693/k
Cp=C0e^-k(t)
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