3. A particular protein heat denatures with a melting temperature Tm = 332 K with an enthalpy of unfolding, AHm = 372 kJmol-¹. (a) What is the entropy of unfolding in kJ mol-1 K-1 at Tm? (b) If ACp is 6.6 kJ mol-1 K-1, at what temperature does the free energy of unfolding (AG unfolding) have the greatest value (i.e. the native state is most stable)? (c) Calculate the value of AG and K at this temperature.
3. A particular protein heat denatures with a melting temperature Tm = 332 K with an enthalpy of unfolding, AHm = 372 kJmol-¹. (a) What is the entropy of unfolding in kJ mol-1 K-1 at Tm? (b) If ACp is 6.6 kJ mol-1 K-1, at what temperature does the free energy of unfolding (AG unfolding) have the greatest value (i.e. the native state is most stable)? (c) Calculate the value of AG and K at this temperature.
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Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
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![3. A particular protein heat denatures with a melting temperature Tm = 332 K with
an enthalpy of unfolding, AHm = 372 kJmol-¹.
(a) What is the entropy of unfolding in kJ mol-1 K-1 at Tm?
(b) If ACp is 6.6 kJ mol-1 K-1, at what temperature does the free energy
of unfolding (AG unfolding) have the greatest value (i.e. the native
state is most stable)?
(c) Calculate the value of AG and K at this temperature.](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F7a918600-ca67-45f5-9085-6eb6f917baf2%2F990a0aef-2a79-4a84-923f-56594b34d41f%2Fsj31ofr_processed.png&w=3840&q=75)
Transcribed Image Text:3. A particular protein heat denatures with a melting temperature Tm = 332 K with
an enthalpy of unfolding, AHm = 372 kJmol-¹.
(a) What is the entropy of unfolding in kJ mol-1 K-1 at Tm?
(b) If ACp is 6.6 kJ mol-1 K-1, at what temperature does the free energy
of unfolding (AG unfolding) have the greatest value (i.e. the native
state is most stable)?
(c) Calculate the value of AG and K at this temperature.
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