7 23. The active site of an enzyme in is shown below. Based on the interaction of the catalytic site of the enzyme to the 17thposition of the steroid ring, what is the sequence of the molecules (inhibitors) based on increasing affinity to the activesite?A. Molecule 1 → Molecule 2 → Molecule 3B. Molecule 3→ Molecule 1→ Molecule 2C. Molecule 3 → Molecule 2 → Molecule 1D. Molecule 2 → Molecule 1→ Molecule 3CatalyticendIle 14Gly 13The 190NADP(H)CONH,Ho.Tyr 153/e 192 Gly 94Met 193/B.Ou 282Leu 9HydrophilicrecognitionendHis 221218S 222Closed24. What is the role of hydrophobic interaction in the active site of this enzyme?A. It keeps the substrate in place during enzymatic reaction.B. It changes the functional group location of the substrate.C. It keeps amino acids in the active site in position.D. It allows permanent binding of substrate to the active site.25. As observed from the molecular structures, the inhibitors need to be structurally similar to estrone. Why is this so?A. The principle of binding of the inhibitor is based on the presence of steroid rings.B. Inhibitor binding needs to establish permanent interactions with the catalytic site.C. Estrogen is a common molecule which makes its structure easy to manipulate.D. The establis hment of hydrogen bonds need to be compatible with the active site.

Name: 7 23. The active site of an enzyme in is shown below. Based on the int
Uploaded: 2024-03-20T06:42:55.000Z
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Description: 7 23. The active site of an enzyme in is shown below. Based on the interaction of the catalytic site of the enzyme to the 17thposition of the steroid ring, what is the sequence of the molecules (inhibitors) based on increasing affinity to the actives